PDF(Pubmed)
Abstract：
Recent emerging zoonotic disease outbreaks, such as that of SARS-CoV-2, have demonstrated the need for wider companion animal disease surveillance. We tested 1000 dogs and cats belonging to employees of a US veterinary hospital network that were exposed to human COVID-19 cases in the household between 1 January 2020 and 10 March 2022 for SARS-CoV-2 and surveyed their owners about clinical signs and risk factors. The seropositivity was 33% for 747 dogs and 27% for 253 cats. Pet seropositivity correlated with the US human case rates over time, exhibiting peaks corresponding with the major COVID-19 surges. Antibodies persisted longer than previously documented (828 days in dogs; 650 days in cats). Increasing age and duration of proximity to infected people were associated with increased seropositivity in dogs but not cats. Cats were more likely to have clinical signs, but an association between seropositivity and the presence of clinical signs was not found in either species.
摘要：
最近新出现的人畜共患疾病爆发，如SARS-CoV-2，已经证明需要更广泛的伴侣动物疾病监测。我们测试了美国兽医医院网络员工的1000只狗和猫，这些狗和猫在2020年1月1日至2022年3月10日期间在家庭中暴露于SARS-CoV-2的人类COVID-19病例，并调查了其所有者的临床体征和风险因素。747只狗的血清阳性率为33％，253只猫的血清阳性率为27％。随着时间的推移，宠物血清阳性与美国人类病例率相关，表现出与主要COVID-19激增相对应的峰值。抗体持续的时间比以前记录的时间长（狗828天；猫650天）。年龄的增加和与感染者接近的持续时间与狗而不是猫的血清阳性增加有关。猫更有可能有临床症状，但是在这两种物种中均未发现血清阳性与临床体征之间的关联。
