PDF(Pubmed)
Abstract：
Chronic obstructive pulmonary disease (COPD) patients are particularly susceptible to respiratory infections like influenza, which exacerbate symptoms and increase healthcare utilization. While smoking cessation and influenza vaccination are recommended preventive measures, their combined impact on healthcare resource utilization is underexplored. The Charlson Comorbidity Index (CCI) assesses comorbidity burden in COPD patients and may influence healthcare outcomes. We conducted a retrospective analysis of 357 COPD patients, evaluating smoking cessation success over one year and influenza vaccination receipt, stratifying patients by CCI scores. Healthcare utilization outcomes included emergency room visits, hospitalizations, and medical expenses. Results showed that 51.82% of patients quit smoking and 59.66% received influenza vaccination, with higher comorbidity prevalence in advanced COPD stages (p = 0.002). Both smoking cessation and influenza vaccination independently correlated with decreased emergency room visits, hospital admissions, days, and costs. Patients who both quit smoking and received influenza vaccination exhibited the lowest healthcare utilization rates. In conclusion, smoking cessation and influenza vaccination significantly reduce healthcare resource utilization in COPD patients, with the combination yielding synergistic benefits, particularly in those with lower CCI scores. Integrating these interventions and comorbidity management in COPD strategies is essential for optimizing patient outcomes and healthcare efficiency.
摘要：
慢性阻塞性肺疾病（COPD）患者特别容易受到呼吸道感染，如流感，这加剧了症状并增加了医疗保健利用率。虽然戒烟和接种流感疫苗是建议的预防措施，它们对医疗资源利用的综合影响未得到充分探索。Charlson合并症指数（CCI）评估COPD患者的合并症负担，并可能影响医疗结果。我们对357例COPD患者进行了回顾性分析，评估戒烟成功超过一年和接种流感疫苗，通过CCI评分对患者进行分层。医疗保健利用结果包括急诊室就诊，住院治疗,和医疗费用。结果显示,51.82%的患者戒烟,59.66%的患者接种流感疫苗,在COPD晚期阶段，合并症患病率较高（p=0.002）。戒烟和流感疫苗接种与急诊室就诊次数的减少独立相关。入院,days,和成本。戒烟和接受流感疫苗接种的患者的医疗保健利用率最低。总之,戒烟和接种流感疫苗会显著降低COPD患者的医疗资源利用率，随着组合产生协同效益，特别是那些CCI分数较低的人。在COPD策略中整合这些干预措施和合并症管理对于优化患者预后和医疗保健效率至关重要。
