关键词: IBD complications clinical application inflammatory bowel disease mechanisms of action protein nutritional support

Mesh : Humans Dietary Proteins / administration & dosage Inflammatory Bowel Diseases / diet therapy therapy Nutritional Support / methods Quality of Life Colitis, Ulcerative / therapy Crohn Disease / therapy diet therapy Nutritional Status

来  源:   DOI:10.3390/nu16142302   PDF(Pubmed)

Abstract:
Inflammatory bowel disease (IBD), a complex chronic inflammatory bowel disorder that includes Crohn\'s disease (CD) and Ulcerative Colitis (UC), has become a globally increasing health concern. Nutrition, as an important factor influencing the occurrence and development of IBD, has attracted more and more attention. As the most important nutrient, protein can not only provide energy and nutrition required by patients, but also help repair damaged intestinal tissue, enhance immunity, and thus alleviate inflammation. Numerous studies have shown that protein nutritional support plays a significant role in the treatment and remission of IBD. This article presents a comprehensive review of the pathogenesis of IBD and analyzes and summarizes the potential mechanisms of protein nutritional support in IBD. Additionally, it provides an overview of the clinical effects of protein nutritional support in IBD and its impact on clinical complications. Research findings reveal that protein nutritional support demonstrates significant benefits in improving clinical symptoms, reducing the risk of complications, and improving quality of life in IBD patients. Therefore, protein nutritional support is expected to provide a new approach for the treatment of IBD.
摘要:
炎症性肠病(IBD),一种复杂的慢性炎症性肠病,包括克罗恩病(CD)和溃疡性结肠炎(UC),已成为全球日益增长的健康问题。营养,作为影响IBD发生发展的重要因素,引起了越来越多的关注。作为最重要的营养素,蛋白质不仅可以提供患者所需的能量和营养,还可以帮助修复受损的肠道组织,增强免疫力,从而减轻炎症。大量研究表明,蛋白质营养支持在IBD的治疗和缓解中起着重要作用。本文对IBD的发病机制进行了全面综述,并对蛋白质营养支持在IBD中的潜在作用机制进行了分析和总结。此外,综述了蛋白质营养支持治疗IBD的临床效果及其对临床并发症的影响。研究结果表明,蛋白质营养支持在改善临床症状方面显示出显著的益处。降低并发症的风险,改善IBD患者的生活质量。因此,蛋白质营养支持有望为IBD的治疗提供新的途径。
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