关键词: cardiovascular modelling computational methods fluid–structure interaction micro elastofluidics microdevices

来  源:   DOI:10.3390/mi15070897   PDF(Pubmed)

Abstract:
Micro elastofluidics is a transformative branch of microfluidics, leveraging the fluid-structure interaction (FSI) at the microscale to enhance the functionality and efficiency of various microdevices. This review paper elucidates the critical role of advanced computational FSI methods in the field of micro elastofluidics. By focusing on the interplay between fluid mechanics and structural responses, these computational methods facilitate the intricate design and optimisation of microdevices such as microvalves, micropumps, and micromixers, which rely on the precise control of fluidic and structural dynamics. In addition, these computational tools extend to the development of biomedical devices, enabling precise particle manipulation and enhancing therapeutic outcomes in cardiovascular applications. Furthermore, this paper addresses the current challenges in computational FSI and highlights the necessity for further development of tools to tackle complex, time-dependent models under microfluidic environments and varying conditions. Our review highlights the expanding potential of FSI in micro elastofluidics, offering a roadmap for future research and development in this promising area.
摘要:
微弹性流体是微流体的一个变革性分支,在微尺度上利用流体-结构相互作用(FSI)来增强各种微器件的功能和效率。这篇综述论文阐明了先进的计算FSI方法在微弹性流体领域的关键作用。通过关注流体力学和结构响应之间的相互作用,这些计算方法促进了微设备的复杂设计和优化,如微型阀,微型泵,和微混合器,依赖于流体动力学和结构动力学的精确控制。此外,这些计算工具延伸到生物医学设备的发展,在心血管应用中实现精确的颗粒操作和增强治疗效果。此外,本文解决了计算FSI当前的挑战,并强调了进一步开发工具以解决复杂问题的必要性,微流体环境和变化条件下的时间依赖性模型。我们的评论强调了FSI在微弹性流体中的扩展潜力,为这个有前途的领域的未来研究和发展提供了路线图。
公众号