PDF(Pubmed)
Abstract：
Basilar artery occlusion (BAO) is a neurological emergency associated with a high risk for adverse outcomes. This review provides evidence on the therapeutic efficacy of intravenous thrombolysis (IVT) and endovascular therapy (EVT) in the treatment of BAO. Historically considered the primary intervention for acute ischemic stroke, IVT has been progressively combined with EVT, which has emerged from recent studies demonstrating clinical benefits, notably in patients presenting with severe stroke. Several randomised controlled trials have shown that EVT improves patient outcomes in select clinical contexts. Future research directions could address therapeutic treatment thresholds, combination strategies, and long-term outcomes.
摘要：
基底动脉闭塞（BAO）是一种神经系统急症，与不良后果的高风险相关。本文综述了静脉溶栓（IVT）和血管内治疗（EVT）治疗BAO的疗效。历史上认为急性缺血性卒中的主要干预措施，IVT已逐步与EVT结合，这是从最近证明临床益处的研究中得出的，尤其是出现严重中风的患者。几项随机对照试验表明，EVT可在选定的临床环境中改善患者的预后。未来的研究方向可以解决治疗阈值，组合战略，和长期结果。
