PDF(Pubmed)
Abstract：
Background: Hidradenitis suppurativa (HS) is a debilitating, chronic inflammatory disease associated with multiple triggers. As the world struggles with the global COVID-19 pandemic, it is important to review the trigger factors for chronically ill HS patients during the COVID-19 pandemic. This work investigates the self-described trigger factors of HS patients that emerged during the COVID-19 outbreak. Methods: We anonymously surveyed 110 HS patients during the SARS-CoV-2 pandemic using a 25-question questionnaire that included trigger factors for deterioration. Demographic, personal, and HS-specific information was also collected to identify potential trigger factors for HS exacerbation. All HS patients were asked if their HS had worsened compared to the time before the pandemic. Results: Compared to before the pandemic, 20% of HS patients (n = 22) reported a worsening of HS. Patients with an HS exacerbation were significantly more likely to avoid contact with a doctor than those without an exacerbation (45.5% vs. 18.2%; p = 0.007). HS involvement, severity, exercise activity, and BMI had no association with worsening HS (p > 0.05). Interestingly, dietary changes and increased consumption of sweets and treats were associated with worsening HS (p = 0.011 and p = 0.013). Specifically, eating more sweets and treats was associated with a 6-fold increased risk of worsening HS. The results suggest that diet has an important influence on HS relapses. Further investigation is needed to determine whether diet is a triggering factor independent of the SARS-CoV-2 pandemic. In addition, gluteal HS involvement was associated with a more than 4.3-fold risk of HS exacerbation. Conclusions: In the management of HS patients, it is important to consider that gluteal involvement and the consumption of sweets are more often associated with deterioration.
摘要：
背景：化脓性汗腺炎（HS）是一种使人衰弱的疾病，与多种触发因素相关的慢性炎症性疾病。随着世界与全球COVID-19大流行作斗争，回顾COVID-19大流行期间慢性HS患者的触发因素非常重要.这项工作调查了在COVID-19爆发期间出现的HS患者的自我描述的触发因素。方法：我们使用25个问题的问卷匿名调查了SARS-CoV-2大流行期间的110名HS患者，其中包括恶化的触发因素。人口统计,个人,我们还收集了HS特异性信息,以确定HS加重的潜在触发因素.询问所有HS患者与大流行前相比，他们的HS是否恶化。结果：与大流行前相比，20％的HS患者（n=22）报告HS恶化。与没有恶化的患者相比，有HS恶化的患者更有可能避免与医生接触(45.5%vs.18.2%；p=0.007）。HS参与，严重程度,锻炼活动,BMI与HS恶化无相关性(p>0.05)。有趣的是,饮食变化和甜食和零食消费增加与HS恶化相关(p=0.011和p=0.013).具体来说,多吃甜食和零食与HS恶化风险增加6倍相关.结果表明，饮食对HS复发有重要影响。需要进一步调查以确定饮食是否是独立于SARS-CoV-2大流行的触发因素。此外,臀肌HS受累与HS恶化的风险超过4.3倍相关。结论:在HS患者的管理中,重要的是要考虑到臀肌受累和甜食的消费更经常与恶化有关。
