PDF(Pubmed)
Abstract：
This prospective case-control study investigated gender-related differences in dry eye symptoms following surgery for involutional ectropion and entropion. A total of 109 patients, aged between 65 and 89, were categorized by eyelid condition and gender. Postoperative assessments included the Tear Film Break-Up Time (TBUT) test, Schirmer I test results, corneal and conjunctival staining, eyelid margin characteristics, and scores from the Ocular Surface Disease Index (OSDI) questionnaire. The analysis revealed notable gender-related differences in dry eye manifestations. Initially, men exhibited lower TBUT scores but higher Schirmer test readings compared to women; however, these disparities diminished over time. No significant gender differences were detected in corneal and conjunctival staining, indicating similar levels of ocular surface damage across genders. Males showed significantly higher values in several eyelid margin characteristics (LMI, LMT) at various postoperative time points. According to the OSDI questionnaire, women experienced more severe symptoms of dry eye both pre- and post-operatively, suggesting a greater subjective symptom burden. When comparing surgical outcomes for ectropion and entropion, both conditions showed improvement in eyelid positioning and dry eye symptoms post-surgery. Despite these improvements, women with either condition reported more severe dry eye symptoms compared to men throughout the postoperative period. This study highlights the gender-specific variations in dry eye symptoms following eyelid malformation surgery and emphasizes the importance of adopting gender-sensitive approaches in postoperative care to improve outcomes and ocular health.
摘要：
这项前瞻性病例对照研究调查了进行性外翻和内翻手术后干眼症状的性别相关差异。共109名患者，年龄在65至89岁之间，按眼睑状况和性别分类。术后评估包括泪膜破裂时间（TBUT）测试，SchirmerI测试结果,角膜和结膜染色，眼睑边缘特征，和来自眼表疾病指数（OSDI）问卷的分数。分析揭示了干眼表现的明显的性别相关差异。最初，与女性相比，男性的TBUT分数较低，但Schirmer测试读数较高；然而，这些差距随着时间的推移而缩小。在角膜和结膜染色中没有检测到显著的性别差异,表明不同性别的眼表损伤水平相似。男性在几个眼睑边缘特征中显示出显着更高的值（LMI，LMT）在术后各个时间点。根据OSDI问卷，女性在手术前后都出现了更严重的干眼症状，表明更大的主观症状负担。当比较外翻和内翻的手术结果时，两种情况均显示眼睑定位和术后干眼症状得到改善.尽管有这些改进,在术后期间,与男性相比,患有上述两种疾病的女性干眼症症状更严重.这项研究强调了眼睑畸形手术后干眼症状的性别特异性变化，并强调了在术后护理中采用性别敏感方法以改善预后和眼部健康的重要性。
