关键词: ROS antioxidant and anti-inflammatory application ferulic acid structure

来  源:   DOI:10.3390/antiox13070853   PDF(Pubmed)

Abstract:
Ferulic acid is a ubiquitous ingredient in cereals, vegetables, fruits and Chinese herbal medicines. Due to the ferulic phenolic nucleus coupled to an extended side chain, it readily forms a resonant-stable phenoxy radical, which explains its potent antioxidant potential. In addition, it also plays an important role in anti-cancer, pro-angiogenesis, anti-thrombosis, neuroprotection, food preservation, anti-aging, and improving the antioxidant performance of livestock and poultry. This review provides a comprehensive summary of the structure, mechanism of antioxidation, application status, molecular mechanism of pharmacological activity, existing problems, and application prospects of ferulic acid and its derivatives. The aim is to establish a theoretical foundation for the utilization of ferulic acid in medicine, food, cosmetics, livestock, and poultry.
摘要:
阿魏酸是谷物中普遍存在的成分,蔬菜,水果和中草药。由于阿魏酸酚类核与延伸的侧链偶联,它很容易形成共振稳定的苯氧基自由基,这解释了它强大的抗氧化潜力。此外,它在抗癌方面也起着重要作用,促血管生成,抗血栓形成,神经保护,食品保存,抗衰老,提高畜禽的抗氧化性能。这篇综述提供了结构的全面总结,抗氧化机制,申请状态,药理活性的分子机制,存在的问题,阿魏酸及其衍生物的应用前景。旨在为阿魏酸在医药上的利用奠定理论基础,食物,化妆品,牲畜,和家禽。
公众号