PDF(Pubmed)
Abstract：
OBJECTIVE: The purpose of this study was to provide gestational age (GA) specific reference ranges for 2-dimensional (2D) placental biometry and 3-dimensional (3D) placental volume between 11 and 14 weeks of gestation.
METHODS: Placental biometry including 2D and 3D variables was calculated in 1142 first-trimester singleton pregnancies with non-complicated outcome between September 2016 and February 2020. Ultrasound datasets were obtained at the time of the first-trimester ultrasound, and 2D basal plate (BP), chorionic plate (CP), placental thickness (PT), and 3D placental volume (PV) were measured following a standardized methodology. Reference ranges for each variable were calculated according to GA and crown-rump-length (CRL).
RESULTS: A total of 1142 uncomplicated pregnancies were considered for analysis. All placental measurements increased significantly between 11 and 14 weeks, especially for PT (39.64%) and PV (64.4%). Reference ranges were constructed for each 2D and 3D first-trimester placental variable using the best-fit regression model for the predicted mean and SD as a function of GA and CRL.
CONCLUSIONS: Reference ranges of 2D placental biometry and 3D placental volume between 11 and 14 weeks of gestation were constructed, generating reference values. Placental biometry showed a progressive increase during the first trimester. This highlights the importance of using reference range charts according to GA.
METHODS: Placental biometry including 2D and 3D variables was calculated in 1142 first-trimester singleton pregnancies with non-complicated outcome between September 2016 and February 2020. Ultrasound datasets were obtained at the time of the first-trimester ultrasound, and 2D basal plate (BP), chorionic plate (CP), placental thickness (PT), and 3D placental volume (PV) were measured following a standardized methodology. Reference ranges for each variable were calculated according to GA and crown-rump-length (CRL).
RESULTS: A total of 1142 uncomplicated pregnancies were considered for analysis. All placental measurements increased significantly between 11 and 14 weeks, especially for PT (39.64%) and PV (64.4%). Reference ranges were constructed for each 2D and 3D first-trimester placental variable using the best-fit regression model for the predicted mean and SD as a function of GA and CRL.
CONCLUSIONS: Reference ranges of 2D placental biometry and 3D placental volume between 11 and 14 weeks of gestation were constructed, generating reference values. Placental biometry showed a progressive increase during the first trimester. This highlights the importance of using reference range charts according to GA.
摘要：
目的：本研究的目的是为妊娠11至14周的2维(2D)胎盘生物特征和3维(3D)胎盘体积提供胎龄(GA)参考范围。
方法：在2016年9月至2020年2月期间，在1142例妊娠早期单胎妊娠中计算了包括2D和3D变量的胎盘生物特征，结果无复杂。超声数据集是在孕早期超声时获得的，和2D基底板(BP)，绒毛膜板（CP），胎盘厚度（PT），和3D胎盘体积(PV)按照标准化方法测量。根据GA和冠部-臀部长度(CRL)计算每个变量的参考范围。
结果：总共1142例无并发症妊娠被考虑进行分析。所有胎盘测量值在11至14周之间显着增加，尤其是PT（39.64%）和PV（64.4%）。使用作为GA和CRL函数的预测平均值和SD的最佳拟合回归模型，为每个2D和3D孕早期胎盘变量构建参考范围。
结论：构建了妊娠11至14周的2D胎盘生物特征和3D胎盘体积的参考范围，生成参考值。胎盘生物特征显示在孕早期逐渐增加。这突出了根据GA使用参考范围图的重要性。
方法：在2016年9月至2020年2月期间，在1142例妊娠早期单胎妊娠中计算了包括2D和3D变量的胎盘生物特征，结果无复杂。超声数据集是在孕早期超声时获得的，和2D基底板(BP)，绒毛膜板（CP），胎盘厚度（PT），和3D胎盘体积(PV)按照标准化方法测量。根据GA和冠部-臀部长度(CRL)计算每个变量的参考范围。
结果：总共1142例无并发症妊娠被考虑进行分析。所有胎盘测量值在11至14周之间显着增加，尤其是PT（39.64%）和PV（64.4%）。使用作为GA和CRL函数的预测平均值和SD的最佳拟合回归模型，为每个2D和3D孕早期胎盘变量构建参考范围。
结论：构建了妊娠11至14周的2D胎盘生物特征和3D胎盘体积的参考范围，生成参考值。胎盘生物特征显示在孕早期逐渐增加。这突出了根据GA使用参考范围图的重要性。
