PDF(Pubmed)
Abstract：
We aimed to explore the effects of two different doses of Zn on the fecal microbiota in pigeons and the correlation between these effects and intestinal immune status. Zn doses affected pigeon growth performance, and pigeons in the T60 (60 mg/kg Zn) and T90 (90 mg/kg Zn) groups exhibited higher villus height and crypt depth in duodenum and ileum compared to the control group, respectively. Supplementation with Zn increased the expression of the IL8, CD798, TJP and NKTR genes (p < 0.05), while enhancing serum immunoglobulin (Ig) G, IgM, and IgA concentrations compared to the control pigeons (p < 0.05). T60 treatment reduced relative Actinobacteriota abundance, while Lactobacillus spp. abundance was highest in the T90 group compared to the two other groups. The core functional genera significantly associated with immune indices in these pigeons were Rhodococcus erythropolis and Lactobacillus ponti. Our findings will help facilitate the application of dietary Zn intake in pig production.
摘要：
我们旨在探讨两种不同剂量的锌对鸽子粪便菌群的影响以及这些影响与肠道免疫状态之间的相关性。锌剂量影响鸽子的生长性能，与对照组相比，T60（60mg/kgZn）和T90（90mg/kgZn）组中的鸽子在十二指肠和回肠中表现出更高的绒毛高度和隐窝深度，分别。锌的补充增加了IL8，CD798，TJP和NKTR基因的表达（p<0.05），同时增强血清免疫球蛋白（Ig）G，IgM,和IgA浓度与对照鸽子相比(p<0.05)。T60处理降低了放线菌的相对丰度，而乳酸菌属。与其他两组相比，T90组的丰度最高。这些鸽子中与免疫指标显着相关的核心功能属是红红球菌和白乳杆菌。我们的发现将有助于促进膳食锌摄入量在猪生产中的应用。
