PDF(Pubmed)
Abstract：
This study aims to understand the cognitive profiles of cerebellar infarction patients and compare them to those with supratentorial infarctions, particularly frontal infarctions. This current study also aims to find reliable assessment tools for detecting cognitive impairment in cerebellar infarction patients. A total of fifty cerebellar infarction patients, sixty supratentorial infarction patients, and thirty-nine healthy controls were recruited. The Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Addenbrooke\'s Cognitive Examination III (ACE-III), and Cerebellar Cognitive Affective Syndrome scale (CCAS-s) were used to assess global cognitive function. An extensive neuropsychological assessment battery was also tested to evaluate the characteristics of each cognitive domain. To assess the features of cognitive function, a comprehensive neuropsychological evaluation tool was also utilized. The cerebral infarction patients demonstrated cognitive impairment comparable to those with frontal infarcts, notably characterized by disturbance in attention and executive function. However, the degree of cognitive impairment was comparatively milder in cerebellar infarction patients. Furthermore, the patients in the cerebellar group had worse scores in the ACE-III and CCAS-s compared to healthy controls. The two assessments also demonstrated a significant area under the curve values, indicating their effectiveness in distinguishing cognitive impairment in cerebellar infarctions. In conclusion, cognitive impairment in a cerebellar infarction resembles frontal lobe dysfunction but is generally mild. It can be accurately assessed using the ACE-III and CCAS-s scales.
摘要：
这项研究旨在了解小脑梗死患者的认知特征，并将其与幕上梗死患者进行比较。尤其是额叶梗塞.本研究还旨在寻找可靠的评估工具来检测小脑梗死患者的认知障碍。共50名小脑梗死患者,60例幕上梗死患者，招募了39名健康对照。迷你精神状态检查（MMSE），蒙特利尔认知评估（MoCA）Addenbrooke的认知检查III(ACE-III)，采用小脑认知情感综合征量表(CCAS-s)评估整体认知功能。还测试了广泛的神经心理学评估电池，以评估每个认知领域的特征。为了评估认知功能的特征，还使用了全面的神经心理学评估工具。脑梗死患者表现出与额叶梗死患者相当的认知障碍，以注意力和执行功能紊乱为特征。然而,小脑梗死患者的认知障碍程度相对较轻。此外，小脑组患者的ACE-III和CCAS-s评分低于健康对照组.两次评估还显示了曲线值下的显着面积，表明它们在区分小脑梗塞的认知障碍方面的有效性。总之,小脑梗死的认知障碍类似于额叶功能障碍，但通常是轻度的。可以使用ACE-III和CCAS-s量表进行准确评估。
