关键词: Bacillus Cereus Antimicrobial therapy Infection control Mortality rate Neonates Sepsis

Mesh : Humans Infant, Newborn Anti-Bacterial Agents / therapeutic use Bacillus cereus / isolation & purification Gram-Positive Bacterial Infections / drug therapy microbiology diagnosis Neonatal Sepsis / microbiology drug therapy diagnosis

来  源:   DOI:10.1186/s12941-024-00712-4   PDF(Pubmed)

Abstract:
Bacillus cereus is a bacterium capable of causing late-onset neonatal sepsis. By analyzing 11 cases, this study investigates the diagnosis, treatment, and prognosis of Bacillus cereus infections, aiming to provide insights into clinical diagnosis and therapy. The study scrutinized 11 instances of late-onset neonatal sepsis, including two fatalities attributable to Bacillus cereus, one accompanied by cerebral hemorrhage. An examination and analysis of these cases\' symptoms, signs, laboratory tests, and treatment processes, along with a review of related literature from 2010 to 2020, revealed a high mortality rate of 41.38% in non-gastrointestinal infections caused by Bacillus cereus. Our findings underscore the critical importance of rapid diagnosis and effective antimicrobial therapy in reducing mortality rates. Once the source of infection is identified, implementing effective infection control measures is essential.
摘要:
蜡样芽孢杆菌是能够引起迟发性新生儿败血症的细菌。通过分析11例,这项研究调查了诊断,治疗,和蜡样芽孢杆菌感染的预后,旨在为临床诊断和治疗提供见解。该研究仔细检查了11例迟发性新生儿败血症,包括两个可归因于蜡样芽孢杆菌的死亡,伴有脑出血。对这些病例的症状进行检查和分析,标志,实验室测试,和治疗过程,结合2010年至2020年的相关文献,发现蜡样芽孢杆菌引起的非胃肠道感染的死亡率高达41.38%。我们的发现强调了快速诊断和有效抗菌治疗在降低死亡率方面的重要性。一旦确定了感染源,实施有效的感染控制措施至关重要。
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