PDF(Pubmed)
Abstract：
There is no consensus about whether relatively large mediastinal tumors (≥ 5.0 cm) are suitable for video-assisted thoracoscopic surgery (VATS). Therefore, this study aimed to compare the efficacy and safety of intercostal approach VATS for large-sized anterior mediastinal tumors (5.0-10.0 cm) with no invasion to the surrounding tissues and organs. A total of 129 patients with anterior mediastinal tumors who received surgery in our hospital between January 2018 and July 2022 were consecutively enrolled. Patients were divided into 2 groups based on mediastinal tumor diameter: Group A (tumor size between 1.0 and 4.9 cm) and Group B (tumor size between 5.0 and 10.0 cm). The primary endpoints were operation time, blood loss, and postoperative pain, and the secondary endpoints were the volume of drainage, drainage duration, postoperative hospital stay, and postoperative complications. Significant differences were found in the volume of drainage between the two groups (Group A: 218.4 ± 140.6, Group B: 398.9 ± 369.3, P < 0.001). However, no differences were found in operation time, blood loss, drainage duration, postoperative hospital stay and duration of postoperative oral analgesics (P > 0.05). In addition, there existed no significant differences in the postoperative complications. Intercostal approach VATS is regarded as a feasible and safe surgical method for large-sized anterior mediastinal tumors (5.0-10.0 cm) with no invasion to the surrounding tissues and organs.
摘要：
关于相对较大的纵隔肿瘤（≥5.0cm）是否适合电视胸腔镜手术（VATS）尚无共识。因此,本研究旨在比较肋间入路VATS治疗大尺寸前纵隔肿瘤(5.0~10.0cm)且未侵犯周围组织和器官的疗效和安全性.连续纳入2018年1月至2022年7月在我院接受手术治疗的129例前纵隔肿瘤患者。根据纵隔肿瘤直径将患者分为两组：A组（肿瘤大小在1.0至4.9cm之间）和B组（肿瘤大小在5.0至10.0cm之间）。主要终点是手术时间，失血,术后疼痛,次要终点是排水量，排水持续时间,术后住院时间,术后并发症。两组之间的引流量存在显着差异（A组：218.4±140.6，B组：398.9±369.3，P<0.001）。然而,手术时间没有差异，失血,排水持续时间,术后住院时间和术后口服镇痛药持续时间(P>0.05)。此外,术后并发症无明显差异。肋间入路VATS被认为是治疗大型前纵隔肿瘤（5.0-10.0cm）的可行且安全的手术方法，对周围组织和器官没有侵犯。
