Abstract:
The following is a narrative review of the fundamentals of optogenetics. It focuses on the advantages and constraints of manipulating the autonomic nervous system by modifying the pathophysiological characteristics that arise in different diseases. Although the use of this technique is currently experimental, we will discuss improvements that have been implemented and identify the necessary measures for potential preclinical translation in the control of the cardiac autonomic nervous system.
摘要:
以下是光遗传学基础知识的叙述性回顾。它着重于通过修改不同疾病中出现的病理生理特征来操纵自主神经系统的优势和约束。虽然这种技术的使用目前是实验性的,我们将讨论已经实施的改进措施,并确定在心脏自主神经系统控制方面潜在的临床前转化的必要措施。