Abstract:
OBJECTIVE: The gubernaculum seems to be the most important anatomical structure in the testicular migration process. The objective of this paper is to review current literature regarding the role of gubernaculum testis nerves in testicular migration. We conducted a comprehensive literature review about the gubernaculum testis innervation. A PubMed database search was performed in April 2024, focusing on gubernaculum testis and cryptorchidism and genitofemoral nerve (GFN) and calcitonin gene-related peptide (CGRP) gene. The gubernaculum has its own nerve supply, the GFN, descending on the anteromedial surface of the psoas muscle from L1-L2 segments. The second phase of testicular descent is regulated by androgens and CGRP, released from the sensory nucleus of the GFN. The GFN doesn\'t directly play a role in testicular migration but there is a theory that shows a regulatory function of this nerve in hormonal action during this process. The gubernaculum testis has important structural alterations during the testicular migration and the genitofemoral nerve and CGRP gene are of great importance in this process. The genitofemoral nerve provides motor innervation to the cremaster muscle and gubernaculum, which helps regulate the position of the testes within the scrotum.
摘要:
目的:引带似乎是睾丸迁移过程中最重要的解剖结构。本文的目的是回顾有关睾丸神经在睾丸迁移中的作用的现有文献。我们对gubernaculum睾丸神经支配进行了全面的文献综述。2024年4月进行了PubMed数据库搜索,重点是指睾丸和隐睾以及生殖股神经(GFN)和降钙素基因相关肽(CGRP)基因。根管有自己的神经供应,GFN,从L1-L2段下降到腰肌的前内侧表面。睾丸下降的第二阶段受雄激素和CGRP调节,从GFN的感觉核释放。GFN在睾丸迁移中不直接发挥作用,但有一种理论表明该神经在此过程中的激素作用中具有调节功能。睾丸根带在睾丸迁移过程中有重要的结构改变,生殖股神经和CGRP基因在此过程中非常重要。生殖股神经为提琴肌和根带提供运动神经支配,这有助于调节睾丸在阴囊内的位置。