PDF(Pubmed)
Abstract：
Trichuris vulpis is a parasite of the large intestine of canids and has a global distribution. Despite its well-established epidemiology, the question of its pathogenicity in dogs remains debated. It has been suggested that younger age and concurrent infection with Ancylostoma caninum may be responsible for more severe clinical presentations. This retrospective study aimed to describe the clinical and diagnostic features of T. vulpis-infected dogs and to compare these findings with dogs infected with both T. vulpis and other intestinal parasites (poly-infected dogs). Forty-five dogs were included, with twenty-five being solely infected by T. vulpis and twenty poly-infected dogs. Only weight loss was more frequent (p = 0.006) in poly-infected dogs compared to T. vulpis mono-infected dogs. No significant differences were observed in laboratory abnormalities between mono-infected and poly-infected dogs. Only diarrhea was more frequent (p = 0.007) in younger dogs compared to adults. The egg shedding pattern was significantly higher (p = 0.04) among adult dogs compared to young ones, and there was a significant positive correlation between egg shedding and age (r = 0.41; p = 0.005). These findings suggest that T. vulpis might be responsible for both clinical signs and laboratory abnormalities in dogs, irrespective of the host\'s age and the presence of other intestinal parasites.
摘要：
毛虫是犬科动物大肠的寄生虫，在全球分布。尽管其流行病学完善，它在狗中的致病性问题仍然存在争议。有人认为，年龄较小和并发的Ancylostomacaninum感染可能是更严重的临床表现的原因。这项回顾性研究旨在描述感染T.vulpis的狗的临床和诊断特征，并将这些发现与感染T.vulpis和其他肠道寄生虫的狗（多感染的狗）进行比较。其中包括45只狗，25只只被T.vulpis感染，20只被多感染的狗感染。与单感染T.vulpis的狗相比，在多感染的狗中，仅体重减轻更频繁（p=0.006）。在单感染和多感染的狗之间的实验室异常中没有观察到显着差异。与成年犬相比，年轻犬中只有腹泻更频繁（p=0.007）。与幼犬相比，成年犬的卵脱落模式明显更高（p=0.04），卵脱落与年龄呈显著正相关(r=0.41;p=0.005)。这些发现表明，T.vulpis可能是造成犬的临床症状和实验室异常的原因。无论宿主的年龄和其他肠道寄生虫的存在。
