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Abstract：
The use of naturally sourced organic materials with chirality, such as the M13 bacteriophage, holds intriguing implications, especially in the field of nanotechnology. The chirality properties of bacteriophages have been demonstrated through numerous studies, particularly in the analysis of liquid crystal phase transitions, developing specific applications. However, exploring the utilization of the M13 bacteriophage as a template for creating chiral nanostructures for optics and sensor applications comes with significant challenges. In this study, the chirality of the M13 bacteriophage was leveraged as a valuable tool for generating helical hybrid structures by combining it with nanoparticles through an evaporation-induced three-dimensional (3D) printing process. Utilizing on the self-assembly property of the M13 bacteriophage, metal nanoparticles were organized into a helical chain under the influence of the M13 bacteriophage at the meniscus interface. External parameters, including nanoparticle shape, the ratio between the bacteriophage and nanoparticles, and pulling speed, were demonstrated as crucial factors affecting the fabrication of helical nanostructures. This study aimed to explore the potential of chiral nanostructure fabrication by utilizing the chirality of the M13 bacteriophage and manipulating external parameters to control the properties of the resulting hybrid structures.
摘要：
使用具有手性的天然来源的有机材料，比如M13噬菌体,具有有趣的含义，尤其是在纳米技术领域。噬菌体的手性特性已经通过许多研究得到证明，特别是在分析液晶相变时，开发特定的应用程序。然而,探索利用M13噬菌体作为创建光学和传感器应用的手性纳米结构的模板带来了重大挑战。在这项研究中,M13噬菌体的手性被用作通过蒸发诱导的三维（3D）打印过程将其与纳米颗粒结合来生成螺旋混合结构的有价值的工具。利用M13噬菌体的自组装特性，在弯月面界面处的M13噬菌体的影响下，金属纳米颗粒被组织成螺旋链。外部参数,包括纳米粒子的形状，噬菌体和纳米颗粒之间的比例，和牵引速度，被证明是影响螺旋纳米结构制造的关键因素。本研究旨在通过利用M13噬菌体的手性和操纵外部参数来控制所得杂化结构的性质来探索手性纳米结构制造的潜力。
