PDF(Pubmed)
Abstract：
Babesia gibsoni is a parasitic protozoan transmitted through tick bites and can cause severe disease in dogs. It can also be transmitted through direct contact with infected blood during dog fights, blood transfusions, and from dam to offspring during the perinatal period, resulting in stillborn or dead newborn puppies. This study aimed to determine the incidence of infection, the viability of newborn puppies, and the degree of B. gibsoni transmission from infected dam to offspring during pregnancy and lactation. Using PCR-based molecular methods, B. gibsoni infection in a pregnant American Pit Bull Terrier and her newborn puppies was confirmed. The incidence of B. gibsoni infection in the litter reached 75%. Out of eight puppies, six were infected with B. gibsoni, and one died. A therapeutic protocol comprising Malarone®, azithromycin, and artesunate was administered to a lactating B. gibsoni-positive bitch. By day 77 after birth, three out of five positive puppies showed negative PCR tests for B. gibsoni, indicating successful treatment through breast milk during nursing. In the two remaining positive puppies, therapy was started and parasitemia was successfully eliminated.
摘要：
gibsoni巴贝斯虫是一种通过蜱叮咬传播的寄生原生动物，可以在狗中引起严重的疾病。它也可以通过在斗狗时直接接触受感染的血液传播，输血,在围产期从大坝到后代，导致死产或死亡的新生小狗。本研究旨在确定感染的发生率，新生小狗的生存能力，以及在怀孕和哺乳期间从感染的大坝传播给后代的吉布索尼杆菌的程度。使用基于PCR的分子方法，证实了怀孕的美国PitBullTerrier和她的新生幼犬中的B.gibsoni感染。产仔数中吉布索尼杆菌感染的发生率达到75％。八只小狗中,六个人感染了B.Gibsoni,一个人死了.包含Malarone®的治疗方案，阿奇霉素,青蒿琥酯给一个哺乳期的吉布索尼阳性母犬服用。出生后77天，五只阳性幼犬中有三只对吉布索尼杆菌的PCR检测呈阴性，表明在护理期间通过母乳成功治疗。在剩下的两只阳性小狗中，开始治疗,成功消除了寄生虫血症.
