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Abstract：
This study aims to understand the functional component compositions of traditional herbal health beverages made from Polygonatum cyrtonema rhizomes and to reveal the pharmacodynamic chemical basis for their claimed health benefits. Two traditional methods, rhizome decoction and rhizome infusion, were used to make health herbal beverages, including \"Huangjin\" tea and \"Huangjin\" wine, respectively. The secondary metabolites of \"Huangjin\" beverages were investigated and compared by widely targeted metabolomics. The results clearly showed that the major functional components in \"Huangjin\" beverages were phenolic acids, flavonoids, and alkaloids. The \"Huangjin\" wine has a greater variety of flavonoids and alkaloids than \"Huangjin\" tea, and the functional components in \"Huangjin\" wine were more abundant than those in \"Huangjin\" tea. Homoisoflavones and amide alkaloids were the dominating flavonoids and alkaloids in \"Huangjin\" wine, respectively. Continuous rhizome infusion could not increase the content of functional components in \"Huangjin\" wine. In conclusion, this study not only provides primary evidence to support the claimed health benefits of \"Huangjin\" beverages but also suggests that making traditional herbal beverages by rhizome infusion has superior health benefits than making them by rhizome decoction, which is attributed to the higher yields of functional components extracted by Chinese liquor than hot water. Therefore, Chinese liquor shows advantages in its use as a superior binary ethanol-water solvent in making herbal health beverages to enhance the solubility of poorly water-soluble functional components.
摘要：
本研究旨在了解黄精根茎制成的传统草药健康饮料的功能成分，并揭示其声称的健康益处的药效学化学基础。两种传统方法，根茎汤和根茎输液，被用来制作健康草药饮料，包括“黄金”茶和“黄金”酒，分别。通过广泛靶向的代谢组学研究和比较“黄金”饮料的次级代谢产物。结果表明，“黄金”饮料中的主要功能成分是酚酸，黄酮类化合物，和生物碱。“黄金”酒的类黄酮和生物碱种类比“黄金”茶更多，“黄金”酒的功能成分比“黄金”茶的功能成分更丰富。高异黄酮和酰胺生物碱是“黄金”葡萄酒中的主要类黄酮和生物碱，分别。连续输注根茎不能增加“黄金”葡萄酒中功能成分的含量。总之,这项研究不仅提供了主要证据来支持“黄金”饮料声称的健康益处，而且还表明，通过根茎输注制作传统草药饮料比通过根茎汤制作具有更好的健康益处，这归因于中国白酒提取的功能成分的产率高于热水。因此,中国白酒在作为一种优良的乙醇-水二元溶剂用于制作草药保健饮料以增强水溶性差的功能成分的溶解度方面表现出优势。
