PDF(Pubmed)
Abstract：
Manuka honey (MH) is considered a superfood mainly because of its various health-promoting properties, including its anti-cancer, anti-inflammatory, and clinically proven antibacterial properties. A unique feature of Manuka honey is the high content of methylglyoxal, which has antibacterial potential. Additionally, it contains bioactive and antioxidant substances such as polyphenols that contribute to its protective effects against oxidative stress. In this study, commercially available Manuka honey was tested for its total polyphenol content and DPPH radical scavenging ability. It was then tested in vitro on human fibroblast cells exposed to UV radiation to assess its potential to protect cells against oxidative stress. The results showed that the honey itself significantly interfered with cell metabolism, and its presence only slightly alleviated the effects of UV exposure. This study also suggested that the MGO content has a minor impact on reducing oxidative stress in UV-irradiated cells and efficiency in scavenging the DPPH radical.
摘要：
麦卢卡蜂蜜（MH）被认为是一种超级食品，主要是因为其各种健康促进特性，包括它的抗癌，抗炎,和临床证明的抗菌性能。麦卢卡蜂蜜的独特之处在于甲基乙二醛含量高，具有抗菌潜力。此外,它含有生物活性和抗氧化物质，如多酚，有助于其对氧化应激的保护作用。在这项研究中,测试了市售麦卢卡蜂蜜的总多酚含量和DPPH自由基清除能力。然后在暴露于紫外线辐射的人成纤维细胞上进行体外测试，以评估其保护细胞免受氧化应激的潜力。结果表明，蜂蜜本身显著干扰细胞代谢，它的存在只是轻微地减轻了紫外线照射的影响。这项研究还表明，MGO含量对减少紫外线照射细胞中的氧化应激和清除DPPH自由基的效率具有较小的影响。
