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Abstract：
Terahertz spectroscopy has unique advantages in the study of biological molecules in aqueous solutions. However, water has a strong absorption capability in the terahertz region. Reducing the amount of liquid could decrease interference with the terahertz wave, which may, however, affect the measurement accuracy. Therefore, it is particularly important to balance the amount and water content of liquid samples. In this work, a terahertz metamaterial sensor based on metallic strips is designed, fabricated, and used to detect reverse micelles. An aqueous confinement environment in reverse micelles can improve the signal-to-noise ratio of the terahertz response. Due to \"water pool\" trapped in reverse micelles, the DOPC (1,2-dioleoyl-sn-glycero-3-phosphocholine) solution and DOPC emulsion can successfully be identified in intensity by terahertz spectroscopy. Combined with the metamaterial sensor, an obvious frequency shift of 30 GHz can be achieved to distinguish the DOPC emulsion (5%) from the DOPC solution. This approach may provide a potential way for improving the sensitivity of detecting trace elements in a buffer solution, thus offering a valuable toolkit toward bioanalytical applications.
摘要：
太赫兹光谱在水溶液中生物分子的研究中具有独特的优势。然而,水在太赫兹区具有很强的吸收能力。减少液体量可以减少对太赫兹波的干扰，可能，然而,影响测量精度。因此,平衡液体样品的量和水含量尤为重要。在这项工作中,设计了一种基于金属条的太赫兹超材料传感器,制作,并用于检测反胶束。反胶束中的水性约束环境可以提高太赫兹响应的信噪比。由于“水池”被困在反胶束中，DOPC（1,2-二油酰基-sn-甘油-3-磷酸胆碱）溶液和DOPC乳液的强度可以通过太赫兹光谱成功鉴定。结合超材料传感器，可以实现30GHz的明显频移以将DOPC乳液(5%)与DOPC溶液区分开。这种方法可以提供一种潜在的方法来提高检测缓冲溶液中微量元素的灵敏度。从而为生物分析应用提供了一个有价值的工具包。
