Abstract：
Acne vulgaris, a prevalent dermatological disorder, frequently affects individuals\' self-perception and general psychosocial functioning. The growing demand for home-based light therapy devices prompted a systematic review to assess the efficacy of visible light in acne treatment. Overall, 35 studies were included, representing 1185 cases of acne vulgaris (mean age: 23.7 years; sex: 63% female). A total of 69% of the included studies were level 2 evidence. Overall, 92% of patients achieved partial remission of their acne lesions using visible light therapy. Among the patients who experienced a partial remission of their acne, 46% experienced a reduction of 0% to 50% in their acne lesions, while 33% and 12% experienced reductions of 51% to 74% and 75% to 99%, respectively. Notably, blue light emerged as the predominant treatment modality in this context, used in around 64% of the cases. A total of 95% of the patients who were treated with blue light experienced a partial clearance of acne lesions; 44% experienced a reduction of 0% to 50% in their acne lesions, while 42% and 9% experienced reductions of 51% to 74% and 75% to 99%, respectively. Overall, the average total lesion count improved by 43% at week 4 compared to the baseline. The average number of treatment sessions was 22 (range 1-112 sessions). On average, treated patients responded within a period of 4 weeks. Commonly reported side effects included skin irritation and erythema. This review highlights the potential of visible light therapy in acne treatment. Head-to-head studies are needed to compare the efficacy of visible light compared to existing therapies for the treatment of acne.
摘要：
寻常痤疮,一种普遍的皮肤病，经常影响个人的自我感知和一般的社会心理功能。对家用光疗设备的需求不断增长，促使人们进行了系统评价，以评估可见光在痤疮治疗中的功效。总的来说,包括35项研究，代表1185例寻常痤疮（平均年龄：23.7岁；性别：63％女性）。总共69%的纳入研究是2级证据。总的来说,92％的患者使用可见光疗法实现了痤疮病变的部分缓解。在经历了痤疮部分缓解的患者中，46％的痤疮病变减少了0％至50％，33%和12%的人经历了51%至74%和75%至99%的下降，分别。值得注意的是,在这种情况下，蓝光成为主要的治疗方式，在大约64%的病例中使用。用蓝光治疗的患者中，有95％的患者经历了痤疮皮损的部分清除；44％的患者的痤疮皮损减少了0％至50％，42%和9%的人经历了51%至74%和75%至99%的下降，分别。总的来说,与基线相比,第4周的平均总病变计数提高了43%.平均治疗次数为22次(范围为1-112次)。平均而言,接受治疗的患者在4周内有反应。通常报道的副作用包括皮肤刺激和红斑。这篇综述强调了可见光疗法在痤疮治疗中的潜力。需要进行头对头研究，以比较可见光与现有治疗痤疮的疗法的疗效。
