PDF(Pubmed)
Abstract：
UNASSIGNED: This study aimed to investigate the results of combined phacoemulsification and viscocanalostomy (phaco-VC) in a six-month follow-up and its relationship with intrascleral lake (IL) using anterior segment optical coherence tomography (AS-OCT) in patients with primary open-angle glaucoma (POAG).
UNASSIGNED: In total, 36 eyes with POAG eligible for phaco-VC were enrolled in this prospective observational study. All patients underwent AS-OCT evaluation and ophthalmologic examination including Goldman tonometry, cup-disc ratio assessment, best corrected visual acuity (BCVA) measurement, and antiglaucoma medication(s) prior to surgery and one, three, and six months after the surgery. The width, length, area, and circumference of the ILs were evaluated using AS-OCT at each follow-up.
UNASSIGNED: A total of 36 eyes of 34 patients with POAG were investigated in this study. According to the results, the mean age of the patients was 70.09 ± 8.73 years, and the majority of the cases were male (n = 23; 63.9%). The mean preoperative intraocular pressure (IOP) was 20.11 ± 7.22 mmHg on 2.47 ± 1.1 medications, and the mean postoperative IOP reduced to 11.11 ± 2.58 mmHg on 0.11 medications, which was statistically significant (P < 0.001). ILs were detectable in all cases which resulted in a 100% qualified success rate. The reduction in the width, area, and circumference of the IL was significant during the six-month follow-up. The relationship between IOP changes and IL parameters on AS-OCT was not significant.
UNASSIGNED: This study evaluated the associations between IL changes and IOP reduction after phaco-VC. A six-month follow-up showed a notable reduction in the IL, but unexpectedly, IOP control did not decline. A reduction in IL diameter, when there is sufficient IOP control, indicates that there may be various IOP lowering mechanisms through VC other than the IL diameters. Further evaluation of VC focusing on long-term changes in IL and Schlemm\'s canal diameter is necessary to explain the precise mechanisms of lowering the IOP.
UNASSIGNED: In total, 36 eyes with POAG eligible for phaco-VC were enrolled in this prospective observational study. All patients underwent AS-OCT evaluation and ophthalmologic examination including Goldman tonometry, cup-disc ratio assessment, best corrected visual acuity (BCVA) measurement, and antiglaucoma medication(s) prior to surgery and one, three, and six months after the surgery. The width, length, area, and circumference of the ILs were evaluated using AS-OCT at each follow-up.
UNASSIGNED: A total of 36 eyes of 34 patients with POAG were investigated in this study. According to the results, the mean age of the patients was 70.09 ± 8.73 years, and the majority of the cases were male (n = 23; 63.9%). The mean preoperative intraocular pressure (IOP) was 20.11 ± 7.22 mmHg on 2.47 ± 1.1 medications, and the mean postoperative IOP reduced to 11.11 ± 2.58 mmHg on 0.11 medications, which was statistically significant (P < 0.001). ILs were detectable in all cases which resulted in a 100% qualified success rate. The reduction in the width, area, and circumference of the IL was significant during the six-month follow-up. The relationship between IOP changes and IL parameters on AS-OCT was not significant.
UNASSIGNED: This study evaluated the associations between IL changes and IOP reduction after phaco-VC. A six-month follow-up showed a notable reduction in the IL, but unexpectedly, IOP control did not decline. A reduction in IL diameter, when there is sufficient IOP control, indicates that there may be various IOP lowering mechanisms through VC other than the IL diameters. Further evaluation of VC focusing on long-term changes in IL and Schlemm\'s canal diameter is necessary to explain the precise mechanisms of lowering the IOP.
摘要：
■本研究旨在探讨原发性开角型青光眼（POAG）患者行白内障超声乳化术和粘管造口术（phaco-VC）联合6个月随访的结果及其与巩膜内湖（IL）的关系。
■总共，这项前瞻性观察研究纳入了符合phaco-VC条件的36只眼POAG。所有患者均接受了AS-OCT评估和眼科检查，包括高盛眼压测量，杯盘比评估，最佳矫正视力（BCVA）测量，和手术前的抗青光眼药物和一种，三,手术后六个月.宽度，长度,area,在每次随访中使用AS-OCT评估IL的周长。
■本研究共调查了34例POAG患者的36只眼。根据结果,患者的平均年龄为70.09±8.73岁，大多数病例为男性(n=23；63.9%)。术前平均眼压（IOP）为20.11±7.22mmHg，使用2.47±1.1药物，使用0.11种药物，术后平均眼压降至11.11±2.58mmHg，有统计学意义(P<0.001)。在所有情况下都可以检测到IL，从而达到100％的合格成功率。宽度的减小，area,在六个月的随访期间，IL的周长显着。眼压变化与AS-OCT上IL参数之间的关系无统计学意义。
■本研究评估了phaco-VC后IL变化与IOP降低之间的关联。6个月的随访显示IL显著降低，但出乎意料的是，IOP控制没有下降。IL直径减小，当有足够的IOP控制时，表明除了IL直径之外，通过VC可能存在各种降低IOP的机制。需要进一步评估关注IL和Schlemm管直径的长期变化的VC，以解释降低IOP的确切机制。
■总共，这项前瞻性观察研究纳入了符合phaco-VC条件的36只眼POAG。所有患者均接受了AS-OCT评估和眼科检查，包括高盛眼压测量，杯盘比评估，最佳矫正视力（BCVA）测量，和手术前的抗青光眼药物和一种，三,手术后六个月.宽度，长度,area,在每次随访中使用AS-OCT评估IL的周长。
■本研究共调查了34例POAG患者的36只眼。根据结果,患者的平均年龄为70.09±8.73岁，大多数病例为男性(n=23；63.9%)。术前平均眼压（IOP）为20.11±7.22mmHg，使用2.47±1.1药物，使用0.11种药物，术后平均眼压降至11.11±2.58mmHg，有统计学意义(P<0.001)。在所有情况下都可以检测到IL，从而达到100％的合格成功率。宽度的减小，area,在六个月的随访期间，IL的周长显着。眼压变化与AS-OCT上IL参数之间的关系无统计学意义。
■本研究评估了phaco-VC后IL变化与IOP降低之间的关联。6个月的随访显示IL显著降低，但出乎意料的是，IOP控制没有下降。IL直径减小，当有足够的IOP控制时，表明除了IL直径之外，通过VC可能存在各种降低IOP的机制。需要进一步评估关注IL和Schlemm管直径的长期变化的VC，以解释降低IOP的确切机制。
