PDF(Pubmed)
Abstract：
Tuberculosis (TB) is still one of the most challenging infectious diseases worldwide. Coinfection with HIV increases the likelihood of extrapulmonary involvement, including the tuberculosis of the central nervous system (CNS-TB). CNS-TB often presents as tuberculomas or tuberculous meningitis. Although tuberculomas can be single or multiple, asymptomatic carriage of numerous tuberculomas is seldom reported. We present a case of a 55-year-old man who carried at least 34 tuberculomas of different sizes asymptomatically before developing and succumbing to tuberculous meningitis. Furthermore, we highlight several possible public health challenges that might have complicated his clinical course, suggesting that future studies also focus on these variables alongside more traditional clinical issues.
摘要：
结核病（TB）仍然是全球最具挑战性的传染病之一。合并感染HIV会增加肺外受累的可能性，包括中枢神经系统结核（CNS-TB）。CNS-TB常表现为结核瘤或结核性脑膜炎。尽管结核瘤可以是单个或多个，许多结核瘤的无症状携带很少报道。我们介绍了一例55岁的男子，该男子在发展并死于结核性脑膜炎之前，无症状地携带了至少34个不同大小的结核瘤。此外，我们强调了几个可能的公共卫生挑战，这些挑战可能会使他的临床课程复杂化，这表明未来的研究也关注这些变量以及更传统的临床问题。
