PDF(Pubmed)
Abstract：
Abiotrophia defectiva, often referred to as nutritionally variant streptococci, is generally a benign part of human microflora, primarily found in the oral cavity, digestive tract, and genitourinary system. However, it can have a significant role in infectious endocarditis (IE). We discuss a case involving a 53-year-old male who displayed serious signs indicative of IE. The individual, who had a history of IgA nephropathy, underwent successful surgical and antibiotic intervention. Given the challenge in treating A. defectiva due to its high antibiotic resistance and the tendency for embolic events and treatment failure, a multidimensional approach involving surgical intervention and specific antibiotic therapy resulted in a successful outcome. This case underlines the need for early identification, immediate treatment, and additional research to understand better and manage A. defectiva endocarditis.
摘要：
营养不良，通常被称为营养变异链球菌，通常是人类微生物的良性部分，主要在口腔中发现，消化道，和泌尿生殖系统。然而,它可以在感染性心内膜炎（IE）中发挥重要作用。我们讨论了一例涉及一名53岁男性的病例，该男性表现出严重的IE迹象。个人，有IgA肾病病史的人,成功进行了手术和抗生素干预。考虑到由于其对抗生素的高耐药性以及栓塞事件和治疗失败的趋势，在治疗上存在挑战。涉及手术干预和特异性抗生素治疗的多维方法导致了成功的结局.这个案例强调了早期识别的必要性,立即治疗,和其他研究，以更好地了解和管理A.
