Abstract：
UNASSIGNED: To describe 3 cases of midline congenital upper lip sinus (MCULS) and review current literature to inform risk of intracranial involvement in the context of this rare congenital facial anomaly.
UNASSIGNED: A limited case series with chart review is presented. A literature search was conducted to review proposed theories of the embryology of MCULS and to determine the relative frequency of cephalic extension.
UNASSIGNED: Including the 3 new cases presented herein, there have been 42 cases of MCULS described in the literature over the past 53 years. Thirty-nine cases (93%) underwent surgical excision, with 2 of these cases (4.7%) demonstrating cephalic extension of the fistula tract beyond the maxillary crest with termination at the anterior skull base. However, 95% (37/39) of surgically excised MCULS cases demonstrated a more limited depth of extension, with termination of the tract at or below the anterior nasal spine.
UNASSIGNED: The MCULS anomaly is rare, with fewer than 50 cases reported in the literature. Only 2 cases have been described with extension of the MCULS superior to the anterior nasal spine and into the nasal septum. It is the authors\' opinion that preoperative neuroimaging is not routinely required for MCULS. However, if extension of the sinus tract beyond the anterior nasal spine is noted intraoperatively, the surgeon should consider aborting the case and obtaining appropriate neuroimaging.
UNASSIGNED: A limited case series with chart review is presented. A literature search was conducted to review proposed theories of the embryology of MCULS and to determine the relative frequency of cephalic extension.
UNASSIGNED: Including the 3 new cases presented herein, there have been 42 cases of MCULS described in the literature over the past 53 years. Thirty-nine cases (93%) underwent surgical excision, with 2 of these cases (4.7%) demonstrating cephalic extension of the fistula tract beyond the maxillary crest with termination at the anterior skull base. However, 95% (37/39) of surgically excised MCULS cases demonstrated a more limited depth of extension, with termination of the tract at or below the anterior nasal spine.
UNASSIGNED: The MCULS anomaly is rare, with fewer than 50 cases reported in the literature. Only 2 cases have been described with extension of the MCULS superior to the anterior nasal spine and into the nasal septum. It is the authors\' opinion that preoperative neuroimaging is not routinely required for MCULS. However, if extension of the sinus tract beyond the anterior nasal spine is noted intraoperatively, the surgeon should consider aborting the case and obtaining appropriate neuroimaging.
摘要：
■描述3例中线先天性上唇窦（MCULS），并回顾当前文献，以告知在这种罕见的先天性面部异常背景下颅内受累的风险。
■介绍了带有图表审查的有限案例系列。进行了文献检索，以回顾拟议的MCULS胚胎学理论，并确定头部延伸的相对频率。
■包括本文提出的3个新案例，在过去的53年中,文献中描述了42例MCULS.39例（93%）接受了手术切除，其中2例（4.7％）表明瘘管向头端延伸超过上颌骨，并终止于前颅底。然而,95％（37/39）的手术切除MCULS病例表现出更有限的延伸深度，在前鼻脊柱处或下方终止管道。
■MCULS异常是罕见的，文献中报道的病例少于50例。仅描述了2例MCULS延伸至鼻前脊柱并进入鼻中隔。作者认为MCULS不常规需要术前神经影像学检查。然而,如果术中发现窦道延伸超过前鼻棘，外科医生应考虑中止病例并进行适当的神经影像学检查。
■介绍了带有图表审查的有限案例系列。进行了文献检索，以回顾拟议的MCULS胚胎学理论，并确定头部延伸的相对频率。
■包括本文提出的3个新案例，在过去的53年中,文献中描述了42例MCULS.39例（93%）接受了手术切除，其中2例（4.7％）表明瘘管向头端延伸超过上颌骨，并终止于前颅底。然而,95％（37/39）的手术切除MCULS病例表现出更有限的延伸深度，在前鼻脊柱处或下方终止管道。
■MCULS异常是罕见的，文献中报道的病例少于50例。仅描述了2例MCULS延伸至鼻前脊柱并进入鼻中隔。作者认为MCULS不常规需要术前神经影像学检查。然而,如果术中发现窦道延伸超过前鼻棘，外科医生应考虑中止病例并进行适当的神经影像学检查。
