关键词: Algorithm Chemoinformatics Prediction Strategy

Mesh : Mutagenicity Tests / methods Mutagens / toxicity Humans Pesticides / toxicity Drug Discovery / methods Animals Biological Assay / methods

来  源:   DOI:10.1016/j.mrgentox.2024.503785

Abstract:
Bioassays are widely used in assessment of mutagenicity. Alternative methods have also been developed, including \"intelligent evaluation\", which depends on the quality of data, strategies, and techniques. CISOC-PSMT is an Ames test prediction system. The strategies and techniques for intelligent evaluation and four applications of CISOC-PSMT are presented; roles in pesticide management, environmental protection, drug discovery, and safety management of chemicals are introduced.
摘要:
生物测定法广泛用于评估诱变性。还开发了替代方法,包括“智能评估”,这取决于数据的质量,战略,和技术。CISOC-PSMT是一个Ames测试预测系统。介绍了智能评估的策略和技术以及CISOC-PSMT的四个应用;在农药管理中的作用,环境保护,药物发现,介绍了化学品的安全管理。
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