泛素结合结构域中的次级相互作用实现连接或底物特异性。
关键词: CP: Molecular biology IKK autophagy mono-ubiquitination optineurin ubiquitin binding domain ubiquitin chain linkage ubiquitin code
Mesh : Humans Substrate Specificity Ubiquitin / metabolism Protein Binding Adaptor Proteins, Signal Transducing / metabolism chemistry Cell Cycle Proteins / metabolism chemistry Zinc Fingers Ubiquitination I-kappa B Kinase / metabolism Ubiquitin-Protein Ligases / metabolism chemistry Protein Domains Phosphorylation HEK293 Cells Membrane Transport Proteins
来 源:
DOI:10.1016/j.celrep.2024.114545
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