Abstract：
Metabolic dysfunction associated fatty liver disease (MAFLD) is an increasing public health problem, affecting one third of the global population. Contrary to conventional wisdom, MAFLD is not exclusive to obese or overweight individuals. Epidemiological studies have revealed a remarkable prevalence among healthy weight individuals, leading investigations into the genetic, lifestyle, and dietary factors that contribute to the development of MAFLD in this population. This shift in perspective requires reconsideration of preventive strategies, diagnostic criteria and therapeutic approaches tailored to address the unique characteristics of MAFLD healthy weight individuals. It also underscores the importance of widespread awareness and education, within the medical community and among the general population, to promote a more inclusive understanding of liver metabolic disorders. With this review, we aim to provide a comprehensive exploration of MAFLD in healthy weight individuals, encompassing epidemiological, pathophysiological, and clinical aspects.
摘要：
代谢功能障碍相关的脂肪肝（MAFLD）是一个日益严重的公共卫生问题，影响了全球三分之一的人口。与传统智慧相反,MAFLD并非肥胖或超重个体独有。流行病学研究表明，健康体重个体的患病率很高，领导对遗传的调查，生活方式,以及导致该人群MAFLD发展的饮食因素。这种观点的转变需要重新考虑预防策略，为解决MAFLD健康体重个体的独特特征而量身定制的诊断标准和治疗方法。它还强调了广泛认识和教育的重要性，在医学界和普通人群中，促进对肝脏代谢紊乱的更全面的理解。通过这次审查,我们的目标是在健康体重的个体中提供MAFLD的全面探索，包括流行病学，病理生理学，和临床方面。
