PDF(Pubmed)
Abstract：
Drug information (DI) provided by hospital pharmacies aims to promote rational and safe drug therapy. While quality assessment for this task is recommended, more knowledge on the factors determining the quality is needed. We aimed to evaluate the impacts of different factors on the quality of DI provided by hospital pharmacies to healthcare professionals. Retrospectively, answers on fictitious enquiries about annual DI tests for German hospital pharmacies over five years were evaluated for content-related and structural requirements. Multivariate analysis was performed for the impact of the enquiry complexity, DI organization (specialized DI center; pharmacist responsible per day; DI on top of other routine tasks), and quality measures (second look; experience of answering pharmacist in DI/on ward; use of documentation database). In 2017-2021, 45, 71, 79, 118, and 122 hospital pharmacies participated. The enquiry complexity had a statistically significant impact on the content-related quality, with poor results for a higher complexity (years 2018/2021, OR 0.25/0.04, p < 0.01). The DI centers achieved better results regarding content-related quality than for a pharmacist responsible per day (OR 0.76/p = 0.65) or DI on top of routine tasks (OR 0.35/p = 0.02). The DI centers scored better in structural quality. The second look showed an overall trend of a better content-related and structural quality. In conclusion, specialized DI centers and second looks are recommended as quality-improving measures. Training for answering complex enquiries should be intensified.
摘要：
医院药房提供的药物信息（DI）旨在促进合理和安全的药物治疗。虽然建议对此任务进行质量评估，需要更多关于决定质量的因素的知识。我们旨在评估不同因素对医院药房向医疗保健专业人员提供的DI质量的影响。回顾过去,对有关德国医院药房五年来的年度DI测试的虚构查询的答案进行了评估，以满足内容相关和结构要求。对查询复杂性的影响进行了多变量分析，DI组织（专门的DI中心；每天负责的药剂师；DI在其他日常任务之上），和质量措施（第二次看；在DI/on病房回答药剂师的经验；使用文档数据库）。在2017-2021年，有45、71、79、118和122家医院药房参加。查询复杂性对内容相关质量有统计上的显著影响，结果不佳，复杂性更高(2018/2021年，OR0.25/0.04，p<0.01)。与每天负责的药剂师（OR0.76/p=0.65）或除常规任务外的DI（OR0.35/p=0.02）相比，DI中心在内容相关质量方面取得了更好的结果。DI中心在结构质量方面得分较高。从第二个角度来看，总体趋势是与内容相关的质量和结构质量更好。总之,建议采用专门的DI中心和二次看点作为提高质量措施。应加强回答复杂询问的培训。
