PDF(Pubmed)
Abstract：
Sleep is a vital process that impacts biological functions such as cell renewal, bone regeneration, and immune system support. Disrupted sleep can interrupt erythropoiesis, leading to fewer red blood cells, reduced haemoglobin concentration, and decreased haematocrit levels, potentially contributing to haematological disorders. This is particularly concerning for shift workers for example firefighters. While previous studies have explored sleep\'s adverse effects on various professions, research specific to firefighters is limited. This study investigates the relationship between sleep quality and haematological parameters among firefighters in Northeast Portugal. From a sample of 201 firefighters, variations in red blood cells, haemoglobin, and haematocrit values were linked to sleep quality. The study utilised non-parametric tests (Wilcoxon-Mann-Whitney, Spearman\'s correlation) to explore the connection between sleep quality and haematological profile. The impact of covariates on haematological parameters was assessed using non-parametric ANCOVA (Quade\'s). A multiple regression analysis was employed to further understand how sleep quality and various confounding variables impact haematological levels. Findings suggest a negative link between sleep quality and haematological levels, meaning that as sleep quality deteriorates, there is a tendency for haematological levels to decrease, as indicated by Spearman\'s correlation (rRBC = -0.157, pRBC = 0.026; rHb = -0.158, pHb = 0.025; rHCT = -0.175, pHCT = 0.013). As observed in scientific literature, the correlation found suggests a possible inhibition of erythropoiesis, the process responsible for red blood cell production. Despite firefighters presenting a haematological profile within the reference range (RBC: 5.1 × 106/mm3 (SD ± 0.4), Hb: 15.6 g/dL (SD ± 1.3), 47% (SD ± 1.0), there is already an observable trend towards lower levels. The analysis of co-variables did not reveal a significant impact of sleep quality on haematological levels. In conclusion, this study underscores the importance of sleep quality in determining haematological parameters among firefighters. Future research should investigate the underlying mechanisms and long-term implications of poor sleep quality on firefighter health. Exploring interventions to enhance sleep quality is vital for evidence-based strategies promoting firefighter well-being.
摘要：
睡眠是影响细胞更新等生物功能的重要过程，骨再生,和免疫系统支持。睡眠中断会中断红细胞生成，导致红细胞减少，血红蛋白浓度降低，血细胞比容水平下降，可能导致血液系统疾病。这对于轮班工人(例如消防员)尤其重要。虽然以前的研究已经探讨了睡眠对各种职业的不利影响，专门针对消防员的研究是有限的。这项研究调查了葡萄牙东北部消防员的睡眠质量与血液学参数之间的关系。从201名消防员的样本中，红细胞的变化，血红蛋白，血细胞比容值与睡眠质量相关。这项研究利用了非参数检验(Wilcoxon-Mann-Whitney，Spearman相关性）探讨睡眠质量与血液学特征之间的联系。使用非参数ANCOVA(Quade's)评估协变量对血液学参数的影响。采用多元回归分析来进一步了解睡眠质量和各种混杂变量如何影响血液学水平。研究结果表明，睡眠质量和血液学水平之间存在负相关，这意味着随着睡眠质量的下降，血液学水平有下降的趋势，如Spearman相关性所示（rRBC=-0.157，pRBC=0.026；rHb=-0.158，pHb=0.025；rHCT=-0.175，pHCT=0.013）。正如在科学文献中观察到的，发现的相关性表明可能抑制红细胞生成，负责红细胞生产的过程。尽管消防员的血液学特征在参考范围内（RBC：5.1×106/mm3（SD±0.4），Hb:15.6g/dL(SD±1.3),47%(标准差±1.0)，已经有明显的下降趋势。共同变量的分析未显示睡眠质量对血液学水平的显着影响。总之,这项研究强调了睡眠质量对确定消防员血液参数的重要性.未来的研究应该调查睡眠质量差对消防员健康的潜在机制和长期影响。探索提高睡眠质量的干预措施对于促进消防员福祉的循证策略至关重要。
