关键词: Anxiety disorders Cognitive-behavioral therapy Efficacy evaluation Habit reversal training Tourette's syndrome

来  源:   DOI:10.5498/wjp.v14.i7.999   PDF(Pubmed)

Abstract:
BACKGROUND: Cognitive-behavioral therapy (CBT) and habit reversal training (HRT) have shown application potential in addressing tic symptoms and comorbid psychiatric conditions. Despite their theoretical potential, empirical evidence on their combined efficacy remains limited.
OBJECTIVE: To evaluate the efficacy of CBT combined with HRT on anxiety disorders in children with Tourette\'s syndrome (TS).
METHODS: Clinical data of children with TS admitted to our hospital from January 2022 to June 2023 were collected, and the patients were grouped into the conventional therapy (control) group and the CBT combined with HRT group. Baseline characteristics, anxiety scores, tic severity scores, treatment adherence, and parental satisfaction were assessed. Statistical analysis was performed using t-tests, chi-square tests, and correlation analysis.
RESULTS: A total of 136 patients, including 65 patients in the control group and 71 patients in the CBT combined with HRT group, were included. The CBT combined with HRT group showed remarkable improvements compared with the control group. Post-intervention assessment revealed a decrease in anxiety scores from 63.52 ± 1.81 to 40.53 ± 1.64 (t = 2.022, P = 0.045), and the Yale Global Tic Severity Scale total score decreased from 22.14 ± 5.67 to 16.28 ± 4.91 (t = 2.288, P = 0.024). Treatment adherence was significantly higher in the CBT combined with HRT group (85.47 ± 7.62%) compared with the control group (82.32 ± 6.54%; t = 2.596, P = 0.010). Parental satisfaction scores were also higher in the CBT combined with HRT group (8.69 ± 1.77) compared with the control group (7.87 ± 1.92; t = 2.592, P = 0.011).
CONCLUSIONS: This study demonstrates that CBT combined with HRT significantly reduces anxiety symptoms and tic severity in children with TS, with higher treatment adherence and parental satisfaction. These findings support the potential application of this comprehensive therapeutic approach for TS treatment.
摘要:
背景:认知行为疗法(CBT)和习惯逆转训练(HRT)已显示出在解决抽动症状和共病精神病方面的应用潜力。尽管他们的理论潜力,关于其综合疗效的经验证据仍然有限。
目的:评价CBT联合HRT治疗Tourette综合征(TS)患儿焦虑障碍的疗效。
方法:收集我院2022年1月至2023年6月收治的TS患儿的临床资料,将患者分为常规治疗(对照组)组和CBT联合HRT组。基线特征,焦虑分数,tic严重程度评分,治疗依从性,并对家长满意度进行了评估。使用t检验进行统计分析,卡方检验,和相关分析。
结果:共有136名患者,其中对照组65例,CBT联合HRT组71例,包括在内。CBT联合HRT组较对照组有显著改善。干预后评估显示焦虑评分从63.52±1.81下降到40.53±1.64(t=2.022,P=0.045),耶鲁全球抽动严重程度量表总分由22.14±5.67降至16.28±4.91(t=2.288,P=0.024)。CBT联合HRT组治疗依从性(85.47±7.62%)明显高于对照组(82.32±6.54%;t=2.596,P=0.010)。CBT联合HRT组家长满意度得分(8.69±1.77)高于对照组(7.87±1.92;t=2.592,P=0.011)。
结论:这项研究表明,CBT联合HRT可显著降低TS患儿的焦虑症状和抽动严重程度,具有更高的治疗依从性和父母满意度。这些发现支持这种综合治疗方法在TS治疗中的潜在应用。
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