PDF(Pubmed)
Abstract：
UNASSIGNED: Morphea, an autoimmune progressive disorder, can significantly impact patient well-being, yet therapeutic options, though expanding, exhibit limited efficacy. A persistent challenge in disease management revolves around monitoring disease activity and gauging treatment effectiveness. To address this, various clinical assessment tools have been devised, each with its inherent limitations. The realm of imaging in morphea has undergone noteworthy expansion, with ultrasonography (US) emerging as an efficacious and cost-effective avenue for quantifying disease activity and evaluating therapeutic outcomes. However, the evidential support for its application remains equivocal. Our aim was to explore and analyze the existing evidence concerning the utility of ultrasound in the management of morphea.
UNASSIGNED: We conducted a comprehensive literature review using PubMed Medline to assess evidence concerning US utility in morphea management.
UNASSIGNED: Sixteen total studies were included in our review.
UNASSIGNED: Although the studies presented carry their own limitations, cumulative findings indicate the potential of ultrasound, particularly when coupled with Doppler, in facilitating staging, assessing disease activity, and longitudinal assessment of therapeutic efficacy in patients with morphea.
UNASSIGNED: We conducted a comprehensive literature review using PubMed Medline to assess evidence concerning US utility in morphea management.
UNASSIGNED: Sixteen total studies were included in our review.
UNASSIGNED: Although the studies presented carry their own limitations, cumulative findings indicate the potential of ultrasound, particularly when coupled with Doppler, in facilitating staging, assessing disease activity, and longitudinal assessment of therapeutic efficacy in patients with morphea.
摘要：
■Morphea,自身免疫性进行性疾病，会显著影响患者的健康，然而治疗选择，虽然扩张，表现出有限的功效。疾病管理的持续挑战围绕监测疾病活动和衡量治疗有效性。为了解决这个问题，已经设计了各种临床评估工具，每个都有其固有的局限性。角膜的成像领域已经经历了值得注意的扩展，超声检查（US）成为量化疾病活动和评估治疗结果的有效且具有成本效益的途径。然而,对其应用的证据支持仍然模棱两可。我们的目的是探索和分析有关超声在硬皮治疗中的应用的现有证据。
■我们使用PubMedMedline进行了全面的文献综述，以评估有关美国在角膜管理中的效用的证据。
■共16项研究纳入我们的综述。
■尽管提出的研究有其自身的局限性，累积发现表明超声的潜力，特别是当与多普勒耦合时，为了促进分期，评估疾病活动，并纵向评估患者的治疗效果。
■我们使用PubMedMedline进行了全面的文献综述，以评估有关美国在角膜管理中的效用的证据。
■共16项研究纳入我们的综述。
■尽管提出的研究有其自身的局限性，累积发现表明超声的潜力，特别是当与多普勒耦合时，为了促进分期，评估疾病活动，并纵向评估患者的治疗效果。
