PDF(Pubmed)
Abstract：
BACKGROUND: Prior case reports and animal studies have reported on potential ophthalmologic complications of babesiosis, but this issue has not previously been addressed in a cohort of patients with babesiosis. This cross-sectional descriptive pilot study evaluated the retinas of patients with acute babesiosis to determine if retinal abnormalities are a feature of the disease.
METHODS: We screened all patients admitted to Yale New Haven Hospital with laboratory confirmed babesiosis during the summer of 2023 and obtained informed consent. Patients were interviewed and underwent pupil dilation and a retinal examination using an indirect ophthalmoscope. Demographic and clinical information were obtained by questionnaire and through chart review.
RESULTS: Ten patients underwent retinal eye exams with results that were generally unremarkable. No study patients showed any signs of retinal inflammation, infection, retinal bleeding, retinal tears, or abnormal vessel formation that could be attributed to infection.
CONCLUSIONS: This small study did not find evidence of retinopathy in patients with babesiosis. Further studies with larger populations, repeated exams, and long term follow up will further elucidate the potential small vessel complications of human babesiosis.
METHODS: We screened all patients admitted to Yale New Haven Hospital with laboratory confirmed babesiosis during the summer of 2023 and obtained informed consent. Patients were interviewed and underwent pupil dilation and a retinal examination using an indirect ophthalmoscope. Demographic and clinical information were obtained by questionnaire and through chart review.
RESULTS: Ten patients underwent retinal eye exams with results that were generally unremarkable. No study patients showed any signs of retinal inflammation, infection, retinal bleeding, retinal tears, or abnormal vessel formation that could be attributed to infection.
CONCLUSIONS: This small study did not find evidence of retinopathy in patients with babesiosis. Further studies with larger populations, repeated exams, and long term follow up will further elucidate the potential small vessel complications of human babesiosis.
摘要：
背景：先前的病例报告和动物研究报道了巴贝斯虫病的潜在眼科并发症，但是这个问题以前在巴贝斯虫病患者队列中没有得到解决.这项横断面描述性试点研究评估了急性巴贝斯病患者的视网膜，以确定视网膜异常是否是该疾病的特征。
方法：我们在2023年夏季筛查了所有在耶鲁纽黑文医院接受实验室确诊的巴贝斯虫病的患者，并获得了知情同意。对患者进行了访谈，并使用间接检眼镜进行了瞳孔扩张和视网膜检查。通过问卷调查和图表审查获得人口统计学和临床信息。
结果：10例患者接受了视网膜眼科检查，结果一般不明显。没有研究患者显示任何视网膜炎症的迹象，感染,视网膜出血,视网膜撕裂,或可能归因于感染的异常血管形成。
结论：这项小型研究没有发现巴贝斯病患者视网膜病变的证据。对更大人群的进一步研究，反复考试,长期随访将进一步阐明人巴贝斯虫病潜在的小血管并发症。
方法：我们在2023年夏季筛查了所有在耶鲁纽黑文医院接受实验室确诊的巴贝斯虫病的患者，并获得了知情同意。对患者进行了访谈，并使用间接检眼镜进行了瞳孔扩张和视网膜检查。通过问卷调查和图表审查获得人口统计学和临床信息。
结果：10例患者接受了视网膜眼科检查，结果一般不明显。没有研究患者显示任何视网膜炎症的迹象，感染,视网膜出血,视网膜撕裂,或可能归因于感染的异常血管形成。
结论：这项小型研究没有发现巴贝斯病患者视网膜病变的证据。对更大人群的进一步研究，反复考试,长期随访将进一步阐明人巴贝斯虫病潜在的小血管并发症。
