PDF(Pubmed)
Abstract：
UNASSIGNED: A robust Health Technology Assessment (HTA) framework is crucial to address the rising burden of healthcare costs and to inform decision-making to promote high-quality health systems. This research aims to describe the HTA methods and mechanisms for the successful implementation of HTA in the WHO South-East Asia region, and contextualize the synthesized evidence relevant to Indian settings.
UNASSIGNED: Realist review involves developing a program theory by conducting a systematic search strategy, screening, study selection, data extraction, and data synthesis. A systematic search for literature will be conducted on PubMed (NCBI), EMBASE (Elsevier), Scopus (Elsevier), Web of Science (Clarivate), and ProQuest Central for identifying the methods used for HTA of health technology interventions. Stakeholder consultations will be conducted to develop a program theory following the Context-Mechanism-Outcome configurations (CMOcs) framework. Searches for primary evidence will be conducted iteratively. Data will be extracted and tested against the programme theory. The proposed realist review will be reported as per the Realist and MEta-narrative Evidence Syntheses: Evolving Standards [RAMESES II] guidelines.
UNASSIGNED: To our knowledge, there has been no comprehensive review conducted to understand the mechanisms of HTA methods in the WHO South-East Asia region. The findings from the realist review will help us understand the mechanisms through which the HTA could work in WHO South-East Asian countries. We will then contextualize the findings obtained from evidence to Indian settings, based on program theory development through stakeholder consultation. A framework will be developed that can be used by policymakers/HTA experts in India for effective implementation of the same.
UNASSIGNED: Realist review involves developing a program theory by conducting a systematic search strategy, screening, study selection, data extraction, and data synthesis. A systematic search for literature will be conducted on PubMed (NCBI), EMBASE (Elsevier), Scopus (Elsevier), Web of Science (Clarivate), and ProQuest Central for identifying the methods used for HTA of health technology interventions. Stakeholder consultations will be conducted to develop a program theory following the Context-Mechanism-Outcome configurations (CMOcs) framework. Searches for primary evidence will be conducted iteratively. Data will be extracted and tested against the programme theory. The proposed realist review will be reported as per the Realist and MEta-narrative Evidence Syntheses: Evolving Standards [RAMESES II] guidelines.
UNASSIGNED: To our knowledge, there has been no comprehensive review conducted to understand the mechanisms of HTA methods in the WHO South-East Asia region. The findings from the realist review will help us understand the mechanisms through which the HTA could work in WHO South-East Asian countries. We will then contextualize the findings obtained from evidence to Indian settings, based on program theory development through stakeholder consultation. A framework will be developed that can be used by policymakers/HTA experts in India for effective implementation of the same.
摘要：
强大的卫生技术评估（HTA）框架对于解决不断增加的医疗成本负担和为决策提供信息以促进高质量的卫生系统至关重要。本研究旨在描述在世卫组织东南亚地区成功实施HTA的HTA方法和机制。并将与印度环境相关的综合证据进行语境化。
■现实主义评论涉及通过进行系统的搜索策略来发展程序理论，筛选,研究选择，数据提取,和数据合成。将在PubMed(NCBI)上进行系统的文献搜索，EMBASE(Elsevier),Scopus(Elsevier),WebofScience(Clarivate),和ProQuestCentral确定用于卫生技术干预的HTA方法。将进行利益相关者协商，以根据上下文机制结果配置（CMCos）框架开发程序理论。主要证据的搜索将迭代进行。将提取数据并根据程序理论进行测试。拟议的现实主义者审查将根据现实主义者和MEta叙事证据综合：不断发展的标准[RAMESESII]指南进行报告。
■据我们所知，尚未进行全面审查以了解世卫组织东南亚区域的HTA方法机制。现实审查的结果将有助于我们了解HTA在世卫组织东南亚国家开展工作的机制。然后，我们将从证据中获得的发现与印度背景联系起来，基于利益相关者咨询的方案理论开发。将制定一个框架，供印度的决策者/HTA专家使用，以有效实施该框架。
■现实主义评论涉及通过进行系统的搜索策略来发展程序理论，筛选,研究选择，数据提取,和数据合成。将在PubMed(NCBI)上进行系统的文献搜索，EMBASE(Elsevier),Scopus(Elsevier),WebofScience(Clarivate),和ProQuestCentral确定用于卫生技术干预的HTA方法。将进行利益相关者协商，以根据上下文机制结果配置（CMCos）框架开发程序理论。主要证据的搜索将迭代进行。将提取数据并根据程序理论进行测试。拟议的现实主义者审查将根据现实主义者和MEta叙事证据综合：不断发展的标准[RAMESESII]指南进行报告。
■据我们所知，尚未进行全面审查以了解世卫组织东南亚区域的HTA方法机制。现实审查的结果将有助于我们了解HTA在世卫组织东南亚国家开展工作的机制。然后，我们将从证据中获得的发现与印度背景联系起来，基于利益相关者咨询的方案理论开发。将制定一个框架，供印度的决策者/HTA专家使用，以有效实施该框架。
