PDF(Pubmed)
Abstract：
UNASSIGNED: Socket preservation is a surgical procedure aimed at preserving the dimensions of the alveolar bone following tooth extraction. It is performed by filling the extraction socket with bone graft material with or without a barrier membrane. Recently, dentine obtained from extracted teeth has been tried as an autograft for socket preservation. Studies have compared the use of dentin to other bone grafts, however, systematic reviews evaluating the efficacy of dentin for socket preservation are limited. Hence, this systematic review protocol is proposed to generate evidence on the efficacy of dentin as a viable alternative to other bone graft materials for socket preservation.
UNASSIGNED: This systematic review protocol was prepared according to the Methodological Expectations of the Cochrane Intervention Reviews (MECIR) guidelines. It will be conducted using the Cochrane Handbook for Systematic Review of Interventions. PubMed, Scopus, Web of Science, EMBASE, Epistemonikos, Cochrane Central, and EBSCO databases and clinical trial registries, will be searched for all randomized controlled trials (RCTs) and non-randomized studies that have used autologous dentin graft (either in particulate/putty, or/matrix form) for socket preservation. The radiographic and clinical assessment of bone and soft tissue healing of the preserved sockets along with patient-related outcomes following surgery will be assessed. The risk of bias assessment of the RCTs and Non-RCTs will be assessed using the \'Cochrane Risk of Bias assessment tool (ROB II) and ROBINS-I respectively. The certainty of evidence will be assessed by the GRADE approach.
UNASSIGNED: This evidence is important for dental clinicians and the public to make an informed decision when choosing graft material for socket preservation. The extracted teeth are considered biological waste; however, this evidence provides scope for using a less invasive autograft for bone regenerative procedures.
UNASSIGNED: PROSPERO: CRD42021201958 (Registered on 15/02/2021).
UNASSIGNED: This systematic review protocol was prepared according to the Methodological Expectations of the Cochrane Intervention Reviews (MECIR) guidelines. It will be conducted using the Cochrane Handbook for Systematic Review of Interventions. PubMed, Scopus, Web of Science, EMBASE, Epistemonikos, Cochrane Central, and EBSCO databases and clinical trial registries, will be searched for all randomized controlled trials (RCTs) and non-randomized studies that have used autologous dentin graft (either in particulate/putty, or/matrix form) for socket preservation. The radiographic and clinical assessment of bone and soft tissue healing of the preserved sockets along with patient-related outcomes following surgery will be assessed. The risk of bias assessment of the RCTs and Non-RCTs will be assessed using the \'Cochrane Risk of Bias assessment tool (ROB II) and ROBINS-I respectively. The certainty of evidence will be assessed by the GRADE approach.
UNASSIGNED: This evidence is important for dental clinicians and the public to make an informed decision when choosing graft material for socket preservation. The extracted teeth are considered biological waste; however, this evidence provides scope for using a less invasive autograft for bone regenerative procedures.
UNASSIGNED: PROSPERO: CRD42021201958 (Registered on 15/02/2021).
摘要：
■插座保存是一种外科手术，旨在保留拔牙后牙槽骨的尺寸。通过在有或没有屏障膜的情况下用骨移植材料填充拔牙槽来进行。最近,从拔牙中获得的牙本质已被尝试作为自体移植来保存牙槽。研究将牙本质的使用与其他骨移植进行了比较，然而,评估牙本质保存牙槽疗效的系统评价是有限的。因此，本系统综述方案旨在提供证据证明牙本质作为其他骨移植材料保存牙槽的可行替代方法的有效性.
■本系统评价方案是根据Cochrane干预评价（MECIR）指南的方法学期望制定的。它将使用Cochrane干预措施系统审查手册进行。PubMed,Scopus,WebofScience,EMBASE,认识论，CochraneCentral,和EBSCO数据库和临床试验注册中心，将搜索所有使用自体牙本质移植的随机对照试验(RCT)和非随机研究(无论是颗粒/腻子，或/矩阵形式)用于插座保存。将评估保留的窝的骨和软组织愈合的影像学和临床评估以及手术后与患者相关的结果。将分别使用Cochrane偏差风险评估工具（ROBII）和ROBINS-I评估RCT和非RCT的偏差风险。证据的确定性将通过等级方法进行评估。
■该证据对于牙科临床医生和公众在选择移植材料进行牙槽保存时做出明智的决定非常重要。拔下的牙齿被认为是生物废物；然而，该证据为使用侵入性较小的自体骨移植进行骨再生手术提供了空间.
■PROSPERO：CRD42021201958（2021年2月15日注册）。
■本系统评价方案是根据Cochrane干预评价（MECIR）指南的方法学期望制定的。它将使用Cochrane干预措施系统审查手册进行。PubMed,Scopus,WebofScience,EMBASE,认识论，CochraneCentral,和EBSCO数据库和临床试验注册中心，将搜索所有使用自体牙本质移植的随机对照试验(RCT)和非随机研究(无论是颗粒/腻子，或/矩阵形式)用于插座保存。将评估保留的窝的骨和软组织愈合的影像学和临床评估以及手术后与患者相关的结果。将分别使用Cochrane偏差风险评估工具（ROBII）和ROBINS-I评估RCT和非RCT的偏差风险。证据的确定性将通过等级方法进行评估。
■该证据对于牙科临床医生和公众在选择移植材料进行牙槽保存时做出明智的决定非常重要。拔下的牙齿被认为是生物废物；然而，该证据为使用侵入性较小的自体骨移植进行骨再生手术提供了空间.
■PROSPERO：CRD42021201958（2021年2月15日注册）。
