Abstract：
This case series describes the clinical, imaging, and histological features of 27 lesions diagnosed as a benign fibrous mass not previously described in veterinary literature. The authors propose the name gingival mucoperiosteal fibroma (GMPF) to describe these fibrous lesions found in dogs. Histologically, GMPF is characterized by a lack of odontogenic tissue and various degrees of ossification. GMPFs affect adult dogs with an average age of 95 months (range 24-156 months) and appear as expansile growths with superficial appearance matching the surrounding gingiva. The mandibular incisive region is the most commonly affected region (n = 13) and most cases have some level of bone proliferation radiographically (n = 14). Histological examination of the masses shows poorly cellular fibrous tissue with thick interwoven collagen fibers. Bony invasion by the mass was not noted, though histological proliferation of bone was seen in 17 lesions. Surgical resection was curative in all cases when performed, and no recurrence was seen at time of follow-up. Fibrous lesions of the oral cavity in dogs are poorly defined and categorized, though numerous lesions have been described in both human and veterinary literature.
摘要：
这个病例系列描述了临床，成像,和27个被诊断为良性纤维团的病变的组织学特征，以前在兽医文献中没有描述。作者提出名称牙龈粘膜骨膜纤维瘤（GMPF）来描述在狗中发现的这些纤维性病变。组织学上,GMPF的特征在于缺乏牙源性组织和不同程度的骨化。GMPF影响平均年龄为95个月（范围24-156个月）的成年犬，并表现为具有表面外观与周围牙龈匹配的扩张性生长。下颌切角区域是最常见的受影响区域（n=13），大多数病例在影像学上有一定程度的骨增生（n=14）。肿块的组织学检查显示，细胞纤维组织较差，胶原纤维交织在一起。没有注意到群众的Bony入侵，尽管在17个病变中可见骨的组织学增生。手术切除在所有情况下都是治愈的，随访时未见复发。狗口腔的纤维病变的定义和分类不明确，尽管在人类和兽医文献中都描述了许多病变。
