混合浸润性导管癌和小叶乳腺癌的空间分子谱分析揭示了内在分子亚型的异质性 ,致癌特征 ,和突变。
关键词: breast cancer mixed ductal–lobular carcinoma single cell omics spatial transcriptomics tumor heterogeneity
Mesh : Humans Female Carcinoma, Lobular / genetics pathology metabolism Carcinoma, Ductal, Breast / genetics pathology metabolism Mutation Breast Neoplasms / genetics pathology metabolism classification Cadherins / genetics metabolism Gene Expression Regulation, Neoplastic Biomarkers, Tumor / genetics metabolism Triple Negative Breast Neoplasms / genetics pathology metabolism Transcriptome Gene Expression Profiling / methods
来 源:
DOI:10.1073/pnas.2322068121
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