Abstract：
The aim of this paper is to study the malonyl ginsenosides in the fresh roots of Panax ginseng. D101 macroporous adsorption resin, ODS, and preparative HPLC were employed to separate the chemical components from the 70% ethanol extract of the fresh roots of P. ginseng, and the structures of the separated compounds were identified based on the data of high-resolution mass spectrometry and nuclear magnetic resonance spectroscopy. Two malonyl ginsenosides were isolated from the fresh roots of P. ginseng and identified as 3-O-\\[6-O-malonyl-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl\\]-20-O-\\[ β-D-xylopyranosyl-(1→4)-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranosyl\\]-dammar-24-ene-3β,12β,20S-triol(1) and 3-O-\\[6-O-malonyl-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl\\]-20-O-\\[ β-D-xylopyranosyl-(1→2)-α-L-arabinofuranosyl-(1→6)-β-D-glucopyranosyl\\]-dammar-24-ene-3β,12β,20S-triol(2), respectively. Compounds 1 and 2 are new compounds isolated from fresh roots of P. ginseng for the first time and named as malonyl ginsenoside-Ra_1 and malonyl ginsenoside-Ra_2, respectively.
摘要：
本文旨在研究人参新鲜根中的丙二酰人参皂苷。D101大孔吸附树脂,ODS,采用制备型高效液相色谱法从人参新鲜根的70%乙醇提取物中分离化学成分，并根据高分辨率质谱和核磁共振波谱数据鉴定了分离化合物的结构。从人参的新鲜根中分离出两种丙二酰人参皂苷，鉴定为3-O-\\[6-O-丙二酰-β-D-吡喃葡萄糖基-(1→2)-β-D-吡喃葡萄糖基\\]-20-O-\\[β-D-吡喃木糖基-(1→4)-β-D-吡喃葡萄糖基12β,20S-三醇(1)和3-O-\[6-O-丙二酰-β-D-吡喃葡萄糖基-(1→2)-β-D-吡喃葡萄糖基\\]-20-O-\\[β-D-吡喃木糖基-(1→2)-α-L-阿拉伯呋喃基-(1→6)-β-D-吡喃葡萄糖基12β,20S-三醇（2），分别。化合物1和2是首次从人参新鲜根中分离得到的新化合物，分别命名为丙二酰人参皂苷-Ra_1和丙二酰人参皂苷-Ra_2。
