PDF(Pubmed)
Abstract：
Inflammatory pseudotumors (IPTs) of the spleen are rare and have often been reported to be associated with Epstein-Barr virus (EBV). Radiographically differentiating IPTs of the spleen from other malignant tumors is challenging, and splenectomy is often performed as a definitive treatment. We report a case of an EBV-associated splenic IPT in a male patient in his 70s. Contrast-enhanced computed tomography (CT) revealed a splenic mass that increased from 2.4 cm to 3.9 cm in diameter over one year. Magnetic resonance imaging (MRI) revealed that the mass showed a slightly high intensity on T1-weighted images and heterogeneous low intensity on T2-weighted images. On dynamic contrast-enhanced MRI, the mass showed weak and gradual inhomogeneous enhancement. A 18F-fluorodeoxyglucose (FDG) positron emission tomography/CT demonstrated increased FDG uptake in the mass. Splenectomy was performed and the pathological diagnosis was EBV-associated IPT. EBV-associated splenic IPT can mimic malignant tumors on imaging, making it challenging to differentiate them from other splenic diseases.
摘要：
脾脏的炎性假瘤（IPT）很少见，并且经常被报道与EB病毒（EBV）有关。放射学将脾脏的IPT与其他恶性肿瘤区分开来是具有挑战性的，脾切除术通常是一种确定的治疗方法。我们报告了一名70多岁的男性患者的EBV相关脾IPT病例。对比增强计算机断层扫描（CT）显示，脾肿块在一年内直径从2.4cm增加到3.9cm。磁共振成像（MRI）显示，肿块在T1加权图像上显示出略高的强度，而在T2加权图像上显示出不均匀的低强度。在动态对比增强MRI上，质量表现出微弱和逐渐的不均匀增强。18F-氟脱氧葡萄糖（FDG）正电子发射断层扫描/CT显示肿块中FDG的摄取增加。行脾切除术，病理诊断为EBV相关性IPT。EBV相关脾IPT可模仿影像学上的恶性肿瘤，这使得将它们与其他脾脏疾病区分开来具有挑战性。
