PDF(Pubmed)
Abstract：
Although neuroendocrine tumours (NETs) are predominantly located in the gastrointestinal tract, pancreas, and lungs, they can also occur in uncommon places such as the biliary system, prostate, breast, head, neck, and even the spinal cord. We present the case of a 30-year-old woman who was referred to the urology clinic for right ureterohydronephrosis. Because the contrast-enhanced CT scan did not show signs of kidney stones or an upper urothelial tract cell carcinoma and was combined with renal scintigraphy, the kidney was not functional, and a left nephrectomy was performed. During the surgery, it was observed that the appendix was attached to the ureter by a tiny tumour. In addition, an appendectomy was also conducted. The pathological test indicated the presence of a NET that had invaded the ureter. The diagnosis was confirmed by immunohistochemical staining. The tissue has been positive for chromogranin and synaptophysin staining. Our work highlights the infrequency and difficulty of diagnosing NETs that invade the ureter. Conducting a thorough histological evaluation in patients with uncertain histopathological diagnoses is essential.
摘要：
尽管神经内分泌肿瘤（NETs）主要位于胃肠道，胰腺,和肺，它们也可能发生在罕见的地方，如胆道系统，前列腺,乳房,头部,脖子,甚至是脊髓.我们介绍了一名30岁的妇女，该妇女因右输尿管肾积水而被转诊到泌尿科诊所。由于对比增强CT扫描未显示肾结石或上尿路上皮细胞癌的征象，并且与肾脏闪烁显像相结合，肾脏没有功能，并进行了左肾切除术。在手术过程中,据观察，阑尾被一个微小的肿瘤附着在输尿管上。此外,还进行了阑尾切除术。病理测试表明存在侵入输尿管的NET。免疫组化染色证实诊断。该组织对嗜铬粒蛋白和突触素染色呈阳性。我们的工作强调了诊断入侵输尿管的NETs的频率和难度。对组织病理学诊断不确定的患者进行彻底的组织学评估至关重要。
