关键词: Antifungal Critically ill patient Immunocompromised patient Invasive aspergillosis Invasive candidiasis Pneumocystis jirovecii

来  源:   DOI:10.1016/j.jointm.2024.01.005   PDF(Pubmed)

Abstract:
Diverse pathogenic fungi can produce severe infections in immunocompromised patients, thereby justifying intensive care unit (ICU) admissions. In some cases, the infections can develop in immunocompromised patients who were previously admitted to the ICU. Aspergillus spp., Pneumocystis jirovecii, Candida spp., and Mucorales are the fungi that are most frequently involved in these infections. Diagnosis continues to be challenging because symptoms and signs are unspecific. Herein, we provide an in-depth review about the diagnosis, with emphasis on recent advances, and treatment of these invasive fungal infections in the ICU setting.
摘要:
多种病原真菌可在免疫功能低下的患者中产生严重的感染,从而证明重症监护病房(ICU)入院是合理的。在某些情况下,感染可发生在先前入住ICU的免疫功能低下患者中.曲霉属。,肺孢子虫jirovecii,念珠菌属。,而毛霉则是这些感染中最常见的真菌。诊断仍然具有挑战性,因为症状和体征不明确。在这里,我们对诊断进行了深入的回顾,强调最近的进展,并在ICU环境中治疗这些侵袭性真菌感染。
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