PDF(Pubmed)
Abstract：
To assess the risk of food allergies in foods processed under the Japanese food labeling system, estimating exposure to hidden allergens is necessary. We assessed exposure to egg protein in foods processed according to the Japanese food labeling system. First, we estimated the concentration distribution of egg protein by Bayesian methods using data from the literature and the measurement of food products with precautional declarations in the labeling margin. We then estimated the food-intake portion-size distribution under two scenarios: soft drink consumption as an example of single, high-intake consumption, and confections, which are frequently consumed by children, as a realistic example of low-intake consumption. Finally, we estimated the distribution of unexpected intake of egg proteins in the form of single consumption. The mean exposure to egg protein under the high-intake scenario was estimated to be 0.0164 mg for 1-15-year-olds, 0.0171 mg for 4-15-year-olds, 0.0181 mg for 7-15-year-olds, and ≥0.0188 mg for 16-year-olds. The mean exposure to egg protein under the low-intake scenario was estimated to be 0.0018 mg for 1-15-year-olds, 0.0019 mg for 4-15-year-olds, 0.0020 mg for 7-15-year-olds, and ≥0.0022 mg for 16-year-olds. Compared to the reference dose of 2.0 mg proposed by the Joint the Food and Agriculture Organization (FAO)/World Health Organization (WHO) Expert Committee, the risk of onset of food allergies due to egg protein contamination from foods without egg labeling is considered to be extremely low under the current Japanese food labeling system.
摘要：
为了评估在日本食品标签制度下加工的食品中食物过敏的风险，估计暴露于隐藏的过敏原是必要的。我们根据日本食品标签系统评估了加工食品中鸡蛋蛋白的暴露情况。首先,我们使用文献中的数据和在标签边缘有预防性声明的食品测量数据，通过贝叶斯方法估计了鸡蛋蛋白的浓度分布。然后，我们估计了两种情况下的食物摄入部分大小分布：软饮料消费作为单一的例子，高摄入消耗，和甜点，儿童经常食用，作为低摄入量消费的一个现实例子。最后,我们估计了以单次消费形式意外摄入的卵蛋白的分布。在高摄入量的情况下，1-15岁儿童对鸡蛋蛋白的平均暴露量估计为0.0164mg，0.0171毫克，4-15岁，0.0181毫克，7-15岁，16岁儿童≥0.0188mg。在低摄入量的情况下，1-15岁儿童对鸡蛋蛋白的平均暴露量估计为0.0018mg，0.0019毫克，4-15岁，0.0020毫克，7-15岁，16岁儿童≥0.0022mg。与粮食及农业组织(粮农组织)/世界卫生组织(世卫组织)联合专家委员会提出的2.0mg参考剂量相比，在目前的日本食品标签制度下，由于没有鸡蛋标签的食物中鸡蛋蛋白污染而引起食物过敏的风险被认为是极低的。
