关键词: Case report adamantinoma recurrence vascularized free fibula graft

来  源:   DOI:10.13107/jocr.2024.v14.i07.4572   PDF(Pubmed)

Abstract:
UNASSIGNED: Adamantinoma is a rare, locally aggressive bone tumor that primarily affects the long bones, with a predilection for the tibia. Although considered a low-grade malignancy, adamantinoma is notorious for its high propensity for recurrence, which poses significant clinical challenges in the management of affected individuals. This case report aims to explore the intricacies of recurrent adamantinoma of the tibia, shedding light on its clinical presentation, diagnostic modalities, treatment strategies, and prognostic factors.
UNASSIGNED: This case report aims to evaluate surgical and functional outcomes of post-excision and reconstruction in recurrent adamantinoma.
UNASSIGNED: This retrospective case report includes the patient who presented in Shaukat Khanum Memorial Cancer Hospital and Research Center Lahore with recurrent adamantinoma. Data were collected after patient\'s written and informed consent, and a retrospective analysis of the patient\'s demographics was done with the Statistical Package for the Social Sciences using the information in the Hospital Information System with a predesigned pro forma. Histology slides were collected from the Department of Pathology. Variables that were included are categorized into demographics, history and examination findings, site, and size of the primary tumor, radiological findings, histological type, stage, and resection margins. The patient underwent wide margin excision and reconstruction with free vascularized fibula graft and his functional outcome was evaluated using the musculoskeletal tumor society score which showed good functional outcome.
UNASSIGNED: Despite therapeutic challenges, wide excision of the tumor followed by free vascularized fibula grafting for reconstruction is a viable option to treat such patients where advanced prosthesis and allografts are not available.
摘要:
Adamantinoma是一种罕见的,主要影响长骨的局部侵袭性骨肿瘤,对胫骨有好感.尽管被认为是低度恶性肿瘤,金刚烷胺瘤因其高复发倾向而臭名昭著,这对受影响个体的管理提出了重大的临床挑战。本病例报告旨在探讨复发性胫骨金刚烷胺瘤的复杂性,阐明其临床表现,诊断方式,治疗策略,和预后因素。
本病例报告旨在评估复发性金刚瘤切除和重建后的手术和功能结果。
本回顾性病例报告包括在ShaukatKhanum纪念肿瘤医院和拉合尔研究中心就诊的复发性金刚烷胺瘤患者。数据收集后,患者的书面和知情同意,和患者的人口统计学的回顾性分析是通过社会科学统计软件包使用医院信息系统中的信息和预先设计的形式。组织学载玻片从病理学系收集。包含的变量被分类为人口统计,历史和检查结果,site,和原发性肿瘤的大小,放射学发现,组织学类型,舞台,和切除边缘。患者接受了自由血管化腓骨移植的广泛切缘切除和重建,并使用肌肉骨骼肿瘤社会评分评估了其功能预后,该评分显示出良好的功能预后。
尽管面临治疗挑战,广泛切除肿瘤,然后进行游离血管化腓骨移植重建是治疗无法获得高级假体和同种异体移植物的患者的可行选择。
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