METHODS: A total of 26 elderly patients with femoral neck fractures who were scanned in 3.0T MRI T2 mapping quantification technique were included. Basing on MRI images, the degree of acetabular cartilage degeneration was classified into Grade 0, 1, 2, 3 and 4, according to the International Cartilage Repair Society (ICRS) scores. In addition, 8 healthy volunteers were included for control group.
RESULTS: By comparison with health population, T2 relaxation values in the anterior, superior, and posterior regions of acetabular cartilage in patients with femoral neck fracture were obviously increased (P < 0.001). Among the patients with femoral neck fractures, there were 16 hip joint with Grade 1-2 (mild degeneration subgroup) and 10 hip joints with Grade 3-4 (severe degeneration subgroup), accounting for 61.54% and 38.46%, respectively. Additionally, T2 relaxation values in the anterior and superior bands of articular cartilage were positively related to the MRI-based grading (P < 0.05); while there was no significant difference of T2 relaxation values in the posterior areas of articular cartilage between severe degeneration subgroup and mild degeneration subgroup (P > 0.05). Importantly, acetabular cartilage degeneration can be detected through signal changes of T2 mapping pseudo-color images.
CONCLUSIONS: 3.0T MRI T2 mapping technology can be used to determine the degree of acetabular cartilage degeneration, which can effectively monitor the disease course.
方法:纳入26例老年股骨颈骨折患者,采用3.0TMRIT2mapping量化技术扫描。基于MRI图像,根据国际软骨修复协会(ICRS)评分,髋臼软骨退变程度分为0,1,2,3和4级.此外,8例健康志愿者作为对照组。
结果:与健康人群相比,前部的T2弛豫值,上级,股骨颈骨折患者髋臼软骨后区明显增高(P<0.001)。在股骨颈骨折患者中,1-2级(轻度变性亚组)髋关节16例,3-4级(重度变性亚组)髋关节10例,占61.54%和38.46%,分别。此外,关节软骨前带和上带的T2松弛值与MRI分级呈正相关(P<0.05);而严重退变亚组和轻度退变亚组的关节软骨后部T2松弛值差异无统计学意义(P>0.05)。重要的是,可以通过T2映射伪彩色图像的信号变化来检测髋臼软骨退变。
结论:3.0TMRIT2标测技术可用于确定髋臼软骨退变的程度,能有效监测病程。