PDF(Pubmed)
Abstract：
Occupational lung/thoracic diseases are a major global public health issue. They comprise a diverse spectrum of health conditions with complex pathology, most of which arise following chronic heavy workplace exposures to various mineral dusts, metal fumes, or following inhaled organic particulate reactions. Many occupational lung diseases could become irreversible; thus accurate diagnosis is mandatory to minimize dust exposure and consequently reduce damage to the respiratory system. Lung biopsy is usually required when exposure history is inconsistent with imaging, in case of unusual or new exposures, in case of unexpected malignancy, and in cases in which there are claims for personal injury and legal compensation. In this paper, we provide an overview of the most frequent occupational lung diseases with a focus on pathological diagnosis. This is a paper that summarizes the expert opinion from a group of European pathologists, together with contributions from other specialists who are crucial for the diagnosis and management of these diseases. Indeed, tight collaboration of all specialists involved in the workup is mandatory as many occupational lung diseases are misdiagnosed or go unrecognized. This document provides a guide for pathologists in practice to facilitate the accurate diagnosis of occupational lung disease. The review article reports relevant topics discussed during an educational course held by expert pathologists, active members of the Pulmonary Pathology Working Group of the European Society of Pathology. The course was endorsed by the University of Padova as a \"winter school\" (selected project in the call for \"Shaping a World-class University\" 2022).
摘要：
职业性肺部/胸部疾病是全球主要的公共卫生问题。它们包括具有复杂病理的各种健康状况，其中大多数是在工作场所长期暴露于各种矿物质粉尘之后出现的，金属烟雾,或吸入有机颗粒反应后。许多职业性肺部疾病可能变得不可逆；因此，必须进行准确的诊断，以最大程度地减少粉尘暴露，从而减少对呼吸系统的损害。当暴露史与影像学不一致时，通常需要进行肺活检，在异常或新的暴露的情况下，在意外的恶性肿瘤的情况下，以及有人身伤害和法律赔偿要求的案件。在本文中,我们概述了最常见的职业性肺部疾病，重点是病理诊断。这是一篇总结了一组欧洲病理学家的专家意见的论文，以及对这些疾病的诊断和管理至关重要的其他专家的贡献。的确,由于许多职业性肺病被误诊或未被识别，因此所有参与检查的专家的紧密合作是强制性的。该文件为病理学家在实践中提供了指导，以促进职业性肺部疾病的准确诊断。这篇评论文章报道了在专家病理学家举办的教育课程中讨论的相关主题，欧洲病理学会肺病理学工作组的活跃成员。该课程被帕多瓦大学认可为“冬季学校”（2022年“塑造世界一流大学”的呼吁中选定的项目）。
