Abstract:
This review delves into relatively less discussed role of alkaline phosphatase (ALP) as an accessible alternative to intact parathyroid hormone (iPTH) in the context of bone health assessment, particularly focussing on its potential boon for underprivileged individuals with chronic kidney disease (CKD) in South Asia. The financial constraints faced by this demographic often hinder regular monitoring of iPTH levels. ALP emerges as a promising surrogate, offering a cost-effective and practical solution for bone health evaluation in resource-constrained settings.
摘要:
这篇综述深入研究了碱性磷酸酶(ALP)在骨骼健康评估中作为完整甲状旁腺激素(iPTH)的可替代方法的相对较少讨论的作用。特别关注其对南亚慢性肾病(CKD)贫困人群的潜在益处。这一人口面临的财政限制往往阻碍了对iPTH水平的定期监测。ALP作为一个有希望的替代品出现,在资源受限的环境中,为骨骼健康评估提供具有成本效益和实用的解决方案。