METHODS: In this study, human bypass grafts were subjected to uniaxial tensile testing, and their elastic modulus was extracted and compared. Additionally, the hyperelastic properties of these grafts were extracted using the Mooney-Rivlin model for use in numerical software.
RESULTS: The average elastic modulus in the circumferential direction for radial artery, mammary artery, and saphenous vein samples were determined to be 1.384 ± 0.268 MPa, 3.108 ± 1.652 MPa, and 7.912 ± 2.509 MPa, respectively. Based on the results of uniaxial tests, the saphenous vein exhibited the highest stiffness among the three vascular tissues.
CONCLUSIONS: The mechanical characterization results of the bypass vessels can be applied to the clinical studies of heart diseases. They may help develop an appropriate treatment approach.
方法:在本研究中,人体旁路移植物进行单轴拉伸试验,提取并比较了它们的弹性模量。此外,这些移植物的超弹性特性是使用Mooney-Rivlin模型提取的,用于数值软件。
结果:桡动脉在圆周方向的平均弹性模量,乳腺动脉,和隐静脉样品测定为1.384±0.268MPa,3.108±1.652MPa,和7.912±2.509MPa,分别。根据单轴试验的结果,在三种血管组织中,隐静脉的硬度最高。
结论:旁路血管的力学表征结果可应用于心脏疾病的临床研究。它们可能有助于开发适当的治疗方法。