关键词: COVID-19 maternal features neonatal outcome pregnancy puerperium

来  源:   DOI:10.4103/jfmpc.jfmpc_1156_23   PDF(Pubmed)

Abstract:
UNASSIGNED: The pandemic of SARS-CoV-2 was a novel situation, there was no conclusive knowledge, particularly concerning its effect on pregnant women and infants. Eminent obstetric organizations have introduced an array of guidelines to assist clinicians in countering this prior unknown outbreak. The primary objective of this study was to summarize the clinical characteristics, complications, and maternal and neonatal outcomes of COVID-19 during pregnancy and puerperium.
UNASSIGNED: This was a cross-sectional observational study conducted in the Outpatient/Emergency/Inpatient or COVID ward in the Department of Obstetrics and Gynaecology, of a tertiary hospital in Nadia district, West Bengal, India, from 1.7.2020 to 30.6.2021 including 104 pregnant or puerperal mothers with laboratory-confirmed, i.e., RT-PCR or Rapid Antigen Test positive reports after informed consent. The obstetric outcome, modes of delivery, and neonatal status including any complications or SNCU admission within six weeks postpartum were recorded.
UNASSIGNED: The majority were in the ≥ 20-24 years age group, primigravida, residents of Nadia with no significant travel or contact history. 73.08% were affected in the third trimester and the comorbidities detected were chiefly anemia (15.38%), hypertensive or chronic liver diseases, and hypothyroidism. 45.19% of the mothers were asymptomatic while the other complaints were fever (18.27%), cough (11.55%), anosmia and/or ageusia (10.58%), sore throat (9.61%), respiratory distress, loose stools, and chest pain. The medical complications were predominantly low SpO2, convulsions, pneumonitis, and two maternal deaths. The obstetric complications were preterm birth (26.9%), pre-eclampsia/eclampsia (17.3%), antepartum (3.9%) and postpartum hemorrhage (4.4%), and sepsis (5.8%). Fourteen mothers had first-trimester termination, 63 had vaginal deliveries, and the rest had cesarean section. Out of 90 neonates, most were in the range of ≥ 2-2.5 kg birth weight and normal 1-min APGAR score. None tested positive for COVID-19 RTPCR and no detectable congenital anomaly or neonatal death was recorded.
摘要:
SARS-CoV-2的大流行是一种新情况,没有确凿的知识,特别是对孕妇和婴儿的影响。著名的产科组织已经引入了一系列指南,以帮助临床医生应对这种先前未知的爆发。这项研究的主要目的是总结临床特征,并发症,妊娠和产褥期COVID-19的母婴结局。
这是一项横断面观察性研究,在妇产科的门诊/急诊/住院或COVID病房进行,纳迪亚区的一家三级医院,西孟加拉邦,印度,从1.7.2020到30.6.2021,包括104名怀孕或产褥期母亲,经实验室确认,即,知情同意后,RT-PCR或快速抗原检测阳性报告。产科结果,交付方式,记录新生儿状况,包括任何并发症或产后6周内SNCU入院情况.
大多数在≥20-24岁年龄组,primigravida,Nadia居民,没有明显的旅行或接触史。73.08%在妊娠晚期受累,检测到的合并症主要是贫血(15.38%),高血压或慢性肝病,和甲状腺功能减退。45.19%的母亲无症状,其他投诉为发烧(18.27%),咳嗽(11.55%),失语症和/或失语症(10.58%),喉咙痛(9.61%),呼吸窘迫,松散的粪便,和胸痛。内科并发症主要是低SpO2,抽搐,肺炎,和两个产妇死亡。产科并发症为早产(26.9%),先兆子痫/子痫(17.3%),产前(3.9%)及产后出血(4.4%),和脓毒症(5.8%)。14名母亲怀孕早期终止妊娠,63人阴道分娩,其余的都是剖腹产.在90名新生儿中,大多数患者出生体重≥2~2.5kg,1分钟APGAR评分正常.没有检测出COVID-19RTPCR呈阳性,也没有记录到可检测到的先天性异常或新生儿死亡。
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