PDF(Pubmed)
Abstract：
OBJECTIVE: After infantile cataract surgery, axial elongation, induces a myopic shift that cannot be fully compensated by corneal flattening and the rate is unpredictable owing to the non-linear growth of the eye. The current prospective study assesses the myopic shift and visual outcomes in children undergoing cataract surgery in infancy over a follow-up period of 5 years.
METHODS: A prospective study conducted at a tertiary eye care center to evaluate the five-year myopic shift, refractive and visual outcomes in infants, who underwent surgery for congenital cataract in infancy. The visual acuity, myopic shift and biometric changes are compared between the aphakia and pseudophakia group.
RESULTS: The mean best-corrected visual acuity (BCVA) recorded in logMAR at 5 years for aphakia group was 0.92±0.44 and for pseudophakia group was 0.66±0.42. (pvalue: 0.002102). The myopic shift was noted to be -5.9+/-5.16 in the aphakia group whereas it was -9.01+/- 3.11 in the pseudophakia group (P value= 0.002101) at 5 years after surgery for infantile cataract.
CONCLUSIONS: IOL implantation in eyes of infants undergoing cataract surgery is feasible in eyes that strictly satisfy the pre-operative inclusion criteria and the visual outcomes in these eyes are better compared to aphakia group at 5 years follow up. Eyes with primary IOL implantation had a higher myopic shift compared to ones without primary IOL implantation. Eyes undergoing primary IOL implantation, need higher under correction compared to the current available formulae.
METHODS: A prospective study conducted at a tertiary eye care center to evaluate the five-year myopic shift, refractive and visual outcomes in infants, who underwent surgery for congenital cataract in infancy. The visual acuity, myopic shift and biometric changes are compared between the aphakia and pseudophakia group.
RESULTS: The mean best-corrected visual acuity (BCVA) recorded in logMAR at 5 years for aphakia group was 0.92±0.44 and for pseudophakia group was 0.66±0.42. (pvalue: 0.002102). The myopic shift was noted to be -5.9+/-5.16 in the aphakia group whereas it was -9.01+/- 3.11 in the pseudophakia group (P value= 0.002101) at 5 years after surgery for infantile cataract.
CONCLUSIONS: IOL implantation in eyes of infants undergoing cataract surgery is feasible in eyes that strictly satisfy the pre-operative inclusion criteria and the visual outcomes in these eyes are better compared to aphakia group at 5 years follow up. Eyes with primary IOL implantation had a higher myopic shift compared to ones without primary IOL implantation. Eyes undergoing primary IOL implantation, need higher under correction compared to the current available formulae.
摘要：
目的：婴儿白内障手术后，轴向伸长,诱导近视偏移，不能通过角膜平坦化来完全补偿，并且由于眼睛的非线性生长，该速率是不可预测的。当前的前瞻性研究评估了在5年的随访期内婴儿期接受白内障手术的儿童的近视转变和视力结果。
方法：在三级眼科护理中心进行的一项前瞻性研究，以评估五年的近视转变，婴儿的屈光和视觉结果，在婴儿期接受了先天性白内障手术。视力，比较了无晶状体和假晶状体组之间的近视变化和生物特征变化。
结果：无晶状体组5年logMAR记录的平均最佳矫正视力（BCVA）为0.92±0.44，假晶状体组为0.66±0.42。（pvalue：0.002102）。在婴儿白内障手术后5年，无晶状体组的近视移位为-5.9/-5.16，而假性晶状体组为-9.01/-3.11（P值=0.002101）。
结论：在严格满足术前纳入标准的白内障手术婴儿眼中植入IOL是可行的，并且在5年随访时，这些眼睛的视力优于无晶状体眼组。与没有初次IOL植入的眼睛相比，初次IOL植入的眼睛的近视移位更高。进行原发性IOL植入的眼睛，与目前可用的公式相比，需要更高的校正。
方法：在三级眼科护理中心进行的一项前瞻性研究，以评估五年的近视转变，婴儿的屈光和视觉结果，在婴儿期接受了先天性白内障手术。视力，比较了无晶状体和假晶状体组之间的近视变化和生物特征变化。
结果：无晶状体组5年logMAR记录的平均最佳矫正视力（BCVA）为0.92±0.44，假晶状体组为0.66±0.42。（pvalue：0.002102）。在婴儿白内障手术后5年，无晶状体组的近视移位为-5.9/-5.16，而假性晶状体组为-9.01/-3.11（P值=0.002101）。
结论：在严格满足术前纳入标准的白内障手术婴儿眼中植入IOL是可行的，并且在5年随访时，这些眼睛的视力优于无晶状体眼组。与没有初次IOL植入的眼睛相比，初次IOL植入的眼睛的近视移位更高。进行原发性IOL植入的眼睛，与目前可用的公式相比，需要更高的校正。
